COL8A1 overexpression promotes glioma cell growth by activating focal adhesion kinase signaling cascade
Abstract We explored expression and biological roles of collagen type VIII alpha-1 chain (COL8A1) in glioma. Bioinformatics analyses unveiled COL8A1 overexpression within glioma tissues correlates with adverse clinical outcomes of patients. COL8A1 overexpression was also detected in local glioma tis...
Saved in:
| Main Authors: | Jin Qian, Haihui Xing, Yin Wang, Chen Li, Hairong Chen, Jun Rong, Chunfa Qian |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-024-00762-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Structural Insight into the Mechanisms of Targeting and Signaling of Focal Adhesion Kinas
by: Gaohua Liu, et al.
Published: (2002-01-01) -
Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion.
by: Patricia Costa, et al.
Published: (2013-01-01) -
<i>O</i>-GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT Pathway
by: Zhiwei Zhang, et al.
Published: (2024-12-01) -
Targeting the integrin beta 1‐focal adhesion kinase axis with artemisinin: Biophysical disruption of cell adhesion, migration, and invasion in tongue cancer
by: Laurensia Danis Anggradita, et al.
Published: (2025-04-01) -
M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats
by: Guiming Liu, et al.
Published: (2025-05-01)