Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity
Coronaviruses cause severe human viral diseases including SARS, MERS and COVID-19. Most recently SARS-CoV-2 virus (causing COVID-19) has led to a pandemic with no successful therapeutics. The SARS-CoV-2 infection relies on trimeric spike (S) proteins to facilitate virus entry into host cells by bind...
Saved in:
| Main Authors: | Jianbo Dong, Betty Huang, Zhejun Jia, Bo Wang, Sachith Gallolu Kankanamalage, Allison Titong, Yue Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
|
| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2020.1768806 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
SINGLE DOMAIN ANTIBODIES AND BIOENGINEERING DRUGS ON THEIR BASIS: NEW OPPORTUNITIES FOR DIAGNOSTICS AND THERAPY
by: E. N. Gorshkova, et al.
Published: (2016-12-01) -
Harnessing antibody-mediated recognition of the intracellular proteome with T cell receptor-like specificity
by: Maya Haus-Cohen, et al.
Published: (2024-11-01) -
Non-Invasive Biomarkers for Early Diagnosis of Kidney Allograft Dysfunction: Current and Future Applications in the Era of Precision Medicine
by: Christina Lazarou, et al.
Published: (2025-02-01) -
Emerging therapeutic agents in multiple myeloma: highlights from the 2024 ASH annual meeting
by: Qing Zhang, et al.
Published: (2025-07-01) -
Identification of a novel biomarker of antibody-mediated rejection in heart transplantation: synergistic effect of anti-nuclear antibodies and de novo donor-specific IgG HLA antibodies
by: Maneesh Kumar Misra, et al.
Published: (2025-04-01)