Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfa...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0093942 |
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| author | Naowarat Tanomsing Mayfong Mayxay Paul N Newton Francois Nosten Christiane Dolecek Tran Tinh Hien Nicholas J White Nicholas P J Day Arjen M Dondorp Mallika Imwong |
| author_facet | Naowarat Tanomsing Mayfong Mayxay Paul N Newton Francois Nosten Christiane Dolecek Tran Tinh Hien Nicholas J White Nicholas P J Day Arjen M Dondorp Mallika Imwong |
| author_sort | Naowarat Tanomsing |
| collection | DOAJ |
| description | The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance. |
| format | Article |
| id | doaj-art-2e5dc923cf5442e2ab163e5d4f9e9230 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-2e5dc923cf5442e2ab163e5d4f9e92302025-08-20T03:46:12ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9394210.1371/journal.pone.0093942Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.Naowarat TanomsingMayfong MayxayPaul N NewtonFrancois NostenChristiane DolecekTran Tinh HienNicholas J WhiteNicholas P J DayArjen M DondorpMallika ImwongThe dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.https://doi.org/10.1371/journal.pone.0093942 |
| spellingShingle | Naowarat Tanomsing Mayfong Mayxay Paul N Newton Francois Nosten Christiane Dolecek Tran Tinh Hien Nicholas J White Nicholas P J Day Arjen M Dondorp Mallika Imwong Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. PLoS ONE |
| title | Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. |
| title_full | Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. |
| title_fullStr | Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. |
| title_full_unstemmed | Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. |
| title_short | Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. |
| title_sort | genetic variability of plasmodium malariae dihydropteroate synthase dhps in four asian countries |
| url | https://doi.org/10.1371/journal.pone.0093942 |
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