Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition

Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition

BackgroundThe natural compound pterostilbene (PTE) has multiple cardiovascular protective effects. However, its effects on pulmonary arterial hypertension (PAH)-associated vascular remodeling remain to be elucidated. This study investigated the effects of PTE on monocrotaline (MCT)-induced PAH in ra...

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Bibliographic Details
Main Authors:	Jie Wang, Yu Zhang, Junjun Liu, Fan Jiang, Xiaopei Cui, Weida Lu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	pterostilbene pulmonary arterial hypertension endothelial-to-mesenchymal transition high mobility group AT-hook SNAI twist
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1621700/full
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