Preclinical evaluation of the RBD-Trimeric vaccine: A novel approach to strengthening biotechnological sovereignty in developing countries against SARS-CoV-2 variants

Preclinical evaluation of the RBD-Trimeric vaccine: A novel approach to strengthening biotechnological sovereignty in developing countries against SARS-CoV-2 variants

New immunogens against emerging new virus variants are essential for controlling new variants. Methods: A preclinical study in which a receptor-binding domain (RBD) trimer was designed in silico with information from the Beta (B.1.351), Omicron (BA.5), and Wuhan 1 variant. A three-dimensional model...

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Bibliographic Details
Main Authors: Luis Flórez, Daniel Echeverri-De la Hoz, Alfonso Calderón, Hector Serrano-Coll, Caty Martinez, Camilo Guzmán, Bertha Gastelbondo, German Arrieta, Ariel Arteta, Tania Márquez, Ricardo Rivero, Salim Máttar
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Travel Medicine and Infectious Disease
Subjects:
Public health
Biotechnology
Social development
Computational biology
Preventive medicine
Vulnerable populations
Online Access:http://www.sciencedirect.com/science/article/pii/S1477893925000262
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