The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates

Evaluating ovarian reserve is crucial in infertility treatment to determine the appropriate approach and predict success rates. Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH) are key parameters commonly used for this purpose, and they usually yield consistent results. A good ova...

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Main Authors: Seray Kaya, Murat Genc, Bensu Bulut, Medine Akkan Oz, Mustafa Ozturk
Format: Article
Language:English
Published: Society of Turaz Bilim 2024-04-01
Series:Medicine Science
Subjects:
Online Access:https://www.medicinescience.org/?mno=224959
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author Seray Kaya
Murat Genc
Bensu Bulut
Medine Akkan Oz
Mustafa Ozturk
author_facet Seray Kaya
Murat Genc
Bensu Bulut
Medine Akkan Oz
Mustafa Ozturk
author_sort Seray Kaya
collection DOAJ
description Evaluating ovarian reserve is crucial in infertility treatment to determine the appropriate approach and predict success rates. Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH) are key parameters commonly used for this purpose, and they usually yield consistent results. A good ovarian reserve is typically indicated when FSH is below 10 IU/ml and AMH is 1 ng/ml or higher. However, in clinical practice, these parameters often conflict, with one suggesting a good ovarian reserve while the other indicates a diminished one. AMH is known to predict oocyte count effectively, but its ability to predict live births is weaker. This study aimed to investigate which parameter is more useful in predicting oocyte count, quality, and live birth outcomes in cases of discordance. This retrospective study was conducted on 82 patients who sought infertility treatment at Assisted Reproductive Techniques Center of Gulhane Training and Research Hospital between January 1, 2016, and December 31, 2020. Data collected included age, AMH and FSH levels, number of retrieved oocytes, mature (M2) oocytes, pregnancy outcomes, and embryos obtained. Statistical analyses were performed using SPSS 25.0. Normal distribution was assessed using the Kolmogorov-Smirnov test and graphical methods. Independent t-tests and One-Way ANOVA were used for normally distributed data, with a significance level set at p=0.05. Patients were divided into two groups: AMH [Med-Science 2024; 13(4.000): 1001-6]
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spelling doaj-art-2e2c86e44e114e3abe99daf317ec3c1b2025-02-07T08:49:24ZengSociety of Turaz BilimMedicine Science2147-06342024-04-011341001610.5455/medscience.2024.10.128224959The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth ratesSeray Kaya0Murat Genc1Bensu Bulut2Medine Akkan Oz3Mustafa Ozturk4Department Of Obstetrics And Gynecology Kulu State Hospital Emergency Medicine Department Ankara Training and Research Hospital Emergency Medicine Department Yenimahalle Training and Research Hospital Emergency Medicine Department Etimesgut Training and Research Hospital Department Of Obstetrics And Gynecology University of Health Sciences Gulhane Training and Research HospitalEvaluating ovarian reserve is crucial in infertility treatment to determine the appropriate approach and predict success rates. Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH) are key parameters commonly used for this purpose, and they usually yield consistent results. A good ovarian reserve is typically indicated when FSH is below 10 IU/ml and AMH is 1 ng/ml or higher. However, in clinical practice, these parameters often conflict, with one suggesting a good ovarian reserve while the other indicates a diminished one. AMH is known to predict oocyte count effectively, but its ability to predict live births is weaker. This study aimed to investigate which parameter is more useful in predicting oocyte count, quality, and live birth outcomes in cases of discordance. This retrospective study was conducted on 82 patients who sought infertility treatment at Assisted Reproductive Techniques Center of Gulhane Training and Research Hospital between January 1, 2016, and December 31, 2020. Data collected included age, AMH and FSH levels, number of retrieved oocytes, mature (M2) oocytes, pregnancy outcomes, and embryos obtained. Statistical analyses were performed using SPSS 25.0. Normal distribution was assessed using the Kolmogorov-Smirnov test and graphical methods. Independent t-tests and One-Way ANOVA were used for normally distributed data, with a significance level set at p=0.05. Patients were divided into two groups: AMH [Med-Science 2024; 13(4.000): 1001-6]https://www.medicinescience.org/?mno=224959anti-mullerian hormonefollicle-stimulating hormoneovarian reservelive birthoocyte quality
spellingShingle Seray Kaya
Murat Genc
Bensu Bulut
Medine Akkan Oz
Mustafa Ozturk
The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
Medicine Science
anti-mullerian hormone
follicle-stimulating hormone
ovarian reserve
live birth
oocyte quality
title The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
title_full The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
title_fullStr The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
title_full_unstemmed The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
title_short The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
title_sort effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates
topic anti-mullerian hormone
follicle-stimulating hormone
ovarian reserve
live birth
oocyte quality
url https://www.medicinescience.org/?mno=224959
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