Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/164235 |
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| author | R. H. Parab B. C. Dixit |
| author_facet | R. H. Parab B. C. Dixit |
| author_sort | R. H. Parab |
| collection | DOAJ |
| description | A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms. |
| format | Article |
| id | doaj-art-2e1f0acbddc240349e84ee7c995fac09 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-2e1f0acbddc240349e84ee7c995fac092025-08-20T03:55:07ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01931188119510.1155/2012/164235Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinolineR. H. Parab0B. C. Dixit1Chemistry Department, V.P. & R.P.T.P Science College, Vallabh Vidyanagar-388120, IndiaChemistry Department, V.P. & R.P.T.P Science College, Vallabh Vidyanagar-388120, IndiaA series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms.http://dx.doi.org/10.1155/2012/164235 |
| spellingShingle | R. H. Parab B. C. Dixit Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline E-Journal of Chemistry |
| title | Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline |
| title_full | Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline |
| title_fullStr | Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline |
| title_full_unstemmed | Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline |
| title_short | Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline |
| title_sort | synthesis characterization and antimicrobial activity of imidazole derivatives based on 2 chloro 7 methyl 3 formylquinoline |
| url | http://dx.doi.org/10.1155/2012/164235 |
| work_keys_str_mv | AT rhparab synthesischaracterizationandantimicrobialactivityofimidazolederivativesbasedon2chloro7methyl3formylquinoline AT bcdixit synthesischaracterizationandantimicrobialactivityofimidazolederivativesbasedon2chloro7methyl3formylquinoline |