Exploring optical coherence tomography parameters in eyes with myopic tilted disc
Abstract Background To investigate the impact of optic disc torsion (ODT), horizontal disc tilt (HDT) angle, and ovality index (OI) on different retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) segments in healthy myopic eyes. Methods ODT and OI were measured from fun...
Saved in:
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Eye and Vision |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40662-024-00411-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846158799492087808 |
|---|---|
| author | Yu Qiao Zhang Xiu Juan Zhang Ru Yue Shen Yuzhou Zhang Fang Yao Tang Simon K. H. Szeto Danny Siu-Chun Ng Ka Wai Kam Alvin L. Young Li Jia Chen Chi Pui Pang Clement C. Tham Jason C. Yam Poemen P. Chan |
| author_facet | Yu Qiao Zhang Xiu Juan Zhang Ru Yue Shen Yuzhou Zhang Fang Yao Tang Simon K. H. Szeto Danny Siu-Chun Ng Ka Wai Kam Alvin L. Young Li Jia Chen Chi Pui Pang Clement C. Tham Jason C. Yam Poemen P. Chan |
| author_sort | Yu Qiao Zhang |
| collection | DOAJ |
| description | Abstract Background To investigate the impact of optic disc torsion (ODT), horizontal disc tilt (HDT) angle, and ovality index (OI) on different retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) segments in healthy myopic eyes. Methods ODT and OI were measured from fundus photographs. HDT angle, peripapillary RNFL, and macular GCIPL were measured by swept-source optical coherence tomography (SS-OCT). The association between optic disc morphology and the RNFL/GCIPL thickness were evaluated, with age and axial length (AL) adjusted. Results Among 530 healthy myopic eyes of 284 participants (mean age: 41.7 years, mean spherical equivalent: − 7.70 D, and mean AL: 26.6 mm), 335 eyes (63.2%) had temporal disc torsion (temporal group) and 195 eyes (36.8%) had nasal disc torsion (nasal group). For the nasal group, a larger OI was associated with thinner superior-to-superonasal GCIPL (β = − 7.465 to − 6.972, both P = 0.024) and temporal RNFL sectors (β = − 49.596 to − 27.748, P ≤ 0.014). For the temporal group, a larger OI was associated with thinner superior-to-nasal (β = − 50.255 to − 22.093, P ≤ 0.006) and thicker temporal RNFL sectors (β = 29.015 to 56.890, P ≤ 0.003). Additionally, a larger HDT angle was associated with thinner superior-to-nasal RNFL sectors (β = − 0.559 to − 0.242, P ≤ 0.036) and thinner superior-to-superotemporal GCIPL sectors (β = − 0.084 to − 0.069, P ≤ 0.037). Conclusions The optic disc tortional direction was associated with the measurement of different RNFL and GCIPL sectors independent of the AL and age. These should be considered when constructing a myopic normative database. |
| format | Article |
| id | doaj-art-2e1e5e90736245d99505e0555a47548e |
| institution | Kabale University |
| issn | 2326-0254 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Eye and Vision |
| spelling | doaj-art-2e1e5e90736245d99505e0555a47548e2024-11-24T12:11:06ZengBMCEye and Vision2326-02542024-11-0111111310.1186/s40662-024-00411-3Exploring optical coherence tomography parameters in eyes with myopic tilted discYu Qiao Zhang0Xiu Juan Zhang1Ru Yue Shen2Yuzhou Zhang3Fang Yao Tang4Simon K. H. Szeto5Danny Siu-Chun Ng6Ka Wai Kam7Alvin L. Young8Li Jia Chen9Chi Pui Pang10Clement C. Tham11Jason C. Yam12Poemen P. Chan13Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye HospitalHong Kong Eye HospitalAbstract Background To investigate the impact of optic disc torsion (ODT), horizontal disc tilt (HDT) angle, and ovality index (OI) on different retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) segments in healthy myopic eyes. Methods ODT and OI were measured from fundus photographs. HDT angle, peripapillary RNFL, and macular GCIPL were measured by swept-source optical coherence tomography (SS-OCT). The association between optic disc morphology and the RNFL/GCIPL thickness were evaluated, with age and axial length (AL) adjusted. Results Among 530 healthy myopic eyes of 284 participants (mean age: 41.7 years, mean spherical equivalent: − 7.70 D, and mean AL: 26.6 mm), 335 eyes (63.2%) had temporal disc torsion (temporal group) and 195 eyes (36.8%) had nasal disc torsion (nasal group). For the nasal group, a larger OI was associated with thinner superior-to-superonasal GCIPL (β = − 7.465 to − 6.972, both P = 0.024) and temporal RNFL sectors (β = − 49.596 to − 27.748, P ≤ 0.014). For the temporal group, a larger OI was associated with thinner superior-to-nasal (β = − 50.255 to − 22.093, P ≤ 0.006) and thicker temporal RNFL sectors (β = 29.015 to 56.890, P ≤ 0.003). Additionally, a larger HDT angle was associated with thinner superior-to-nasal RNFL sectors (β = − 0.559 to − 0.242, P ≤ 0.036) and thinner superior-to-superotemporal GCIPL sectors (β = − 0.084 to − 0.069, P ≤ 0.037). Conclusions The optic disc tortional direction was associated with the measurement of different RNFL and GCIPL sectors independent of the AL and age. These should be considered when constructing a myopic normative database.https://doi.org/10.1186/s40662-024-00411-3Myopic tilted discMyopiaOptical coherence tomography |
| spellingShingle | Yu Qiao Zhang Xiu Juan Zhang Ru Yue Shen Yuzhou Zhang Fang Yao Tang Simon K. H. Szeto Danny Siu-Chun Ng Ka Wai Kam Alvin L. Young Li Jia Chen Chi Pui Pang Clement C. Tham Jason C. Yam Poemen P. Chan Exploring optical coherence tomography parameters in eyes with myopic tilted disc Eye and Vision Myopic tilted disc Myopia Optical coherence tomography |
| title | Exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| title_full | Exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| title_fullStr | Exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| title_full_unstemmed | Exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| title_short | Exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| title_sort | exploring optical coherence tomography parameters in eyes with myopic tilted disc |
| topic | Myopic tilted disc Myopia Optical coherence tomography |
| url | https://doi.org/10.1186/s40662-024-00411-3 |
| work_keys_str_mv | AT yuqiaozhang exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT xiujuanzhang exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT ruyueshen exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT yuzhouzhang exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT fangyaotang exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT simonkhszeto exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT dannysiuchunng exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT kawaikam exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT alvinlyoung exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT lijiachen exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT chipuipang exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT clementctham exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT jasoncyam exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc AT poemenpchan exploringopticalcoherencetomographyparametersineyeswithmyopictilteddisc |