Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients
Aim: to obtain a causal relationship between changes in plasma sodium levels and increased extracellular fluid volume between post-hemodialysis and pre-hemodialysis on the following day or plasma sodium serves as a predictor of extracellular fluid volume. Methods: the study was conducted on 40 subj...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2014-10-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | https://www.actamedindones.org/index.php/ijim/article/view/106 |
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| author | Parlindungan Siregar |
| author_facet | Parlindungan Siregar |
| author_sort | Parlindungan Siregar |
| collection | DOAJ |
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Aim: to obtain a causal relationship between changes in plasma sodium levels and increased extracellular fluid volume between post-hemodialysis and pre-hemodialysis on the following day or plasma sodium serves as a predictor of extracellular fluid volume. Methods: the study was conducted on 40 subjects randomly selected from the 247 chronic hemodialysis patients in Hemodialysis Unit of Nephrology and Hypertension Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital that met the inclusion and exclusion criteria. Their plasma sodium levels, post-hemodialysis weight and pre-hemodialysis weight on the following day were examined. Results: There was no significant difference in the plasma sodium levels between post-hemodialysis and pre-hemodialysis on the following day. However, there was a considerable differences between post-hemodialysis weight and pre-hemodialysis weight on the following day (p = 0.0000). In regression analysis that were conducted on the relationship between the difference in pre-hemodialysis sodium levels subtracted by previous post-hemodiaysis sodium levels (Y) and the difference in pre-hemodialysis weight subtractted by previous post-hemodialysis weight (X), a significant causal relationship was found with the regression formula of Y = - 2.205 + 0.937 X. Conclusion: plasma sodium levels in chronic hemodialysis patients can be used as predictors of body fluid volume or extracellular fluid volume. At each dialysis unit, the recommended weight gain for the patients are 2.5 kg-2.9 kg, in order to prevent a significant decrease in plasma sodium levels that could lead to mortality.
Key words: plasma sodium, weight gain, hemodialysis.
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| format | Article |
| id | doaj-art-2e1d6852da684d97a13197e9ac68c79e |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2014-10-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-2e1d6852da684d97a13197e9ac68c79e2025-08-20T03:08:33ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322014-10-01464Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis PatientsParlindungan Siregar0Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia Aim: to obtain a causal relationship between changes in plasma sodium levels and increased extracellular fluid volume between post-hemodialysis and pre-hemodialysis on the following day or plasma sodium serves as a predictor of extracellular fluid volume. Methods: the study was conducted on 40 subjects randomly selected from the 247 chronic hemodialysis patients in Hemodialysis Unit of Nephrology and Hypertension Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital that met the inclusion and exclusion criteria. Their plasma sodium levels, post-hemodialysis weight and pre-hemodialysis weight on the following day were examined. Results: There was no significant difference in the plasma sodium levels between post-hemodialysis and pre-hemodialysis on the following day. However, there was a considerable differences between post-hemodialysis weight and pre-hemodialysis weight on the following day (p = 0.0000). In regression analysis that were conducted on the relationship between the difference in pre-hemodialysis sodium levels subtracted by previous post-hemodiaysis sodium levels (Y) and the difference in pre-hemodialysis weight subtractted by previous post-hemodialysis weight (X), a significant causal relationship was found with the regression formula of Y = - 2.205 + 0.937 X. Conclusion: plasma sodium levels in chronic hemodialysis patients can be used as predictors of body fluid volume or extracellular fluid volume. At each dialysis unit, the recommended weight gain for the patients are 2.5 kg-2.9 kg, in order to prevent a significant decrease in plasma sodium levels that could lead to mortality. Key words: plasma sodium, weight gain, hemodialysis. https://www.actamedindones.org/index.php/ijim/article/view/106 |
| spellingShingle | Parlindungan Siregar Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients Acta Medica Indonesiana |
| title | Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients |
| title_full | Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients |
| title_fullStr | Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients |
| title_full_unstemmed | Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients |
| title_short | Plasma Sodium in Relation with the Extracellular Fluid Volume in Chronic Hemodialysis Patients |
| title_sort | plasma sodium in relation with the extracellular fluid volume in chronic hemodialysis patients |
| url | https://www.actamedindones.org/index.php/ijim/article/view/106 |
| work_keys_str_mv | AT parlindungansiregar plasmasodiuminrelationwiththeextracellularfluidvolumeinchronichemodialysispatients |