Stem cells propagate their DNA by random segregation in the flatworm Macrostomum lignano.

Stem cells propagate their DNA by random segregation in the flatworm Macrostomum lignano.

Adult stem cells are proposed to have acquired special features to prevent an accumulation of DNA-replication errors. Two such mechanisms, frequently suggested to serve this goal are cellular quiescence, and non-random segregation of DNA strands during stem cell division, a theory designated as the...

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Bibliographic Details
Main Authors: Freija Verdoodt, Maxime Willems, Stijn Mouton, Katrien De Mulder, Wim Bert, Wouter Houthoofd, Julian Smith, Peter Ladurner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0030227&type=printable
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