Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis
Only one case report has previously described a patient with multiple sclerosis and a type 1 Brugada pattern on the electrocardiogram. Patients with multiple sclerosis have several neurological deficits including sensory symptoms, acute or subacute motor weakness, gait disturbance, and balance probl...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2019/3937248 |
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| _version_ | 1832554676724170752 |
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| author | Michel Ibrahim Garly Saint-Croix Rosario Colombo |
| author_facet | Michel Ibrahim Garly Saint-Croix Rosario Colombo |
| author_sort | Michel Ibrahim |
| collection | DOAJ |
| description | Only one case report has previously described a patient with multiple sclerosis and a type 1 Brugada pattern on the electrocardiogram. Patients with multiple sclerosis have several neurological deficits including sensory symptoms, acute or subacute motor weakness, gait disturbance, and balance problems that may lead to an increased risk of falls. Concurrent autonomic dysfunction and neurologic consequences of multiple sclerosis may precipitate both mechanical falls and falls with loss of consciousness. While mechanistically different, the type 1 Brugada pattern presents similarly with syncope due to an insufficient cardiac output during dysrhythmia. In such patients, intracardiac defibrillators have shown to prevent sudden cardiac death in patients with the Brugada syndrome. In light of these similarly presenting but unique clinical entities, MS patients who develop a syncopal event in the setting of a spontaneous type I Brugada pattern pose a diagnostic and therapeutic dilemma. This case illustrates an approach to the risks and benefits of an ICD placement in an MS patient with the type 1 Brugada pattern. |
| format | Article |
| id | doaj-art-2e113fbf81f24bbdb532c743b42f3bce |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-2e113fbf81f24bbdb532c743b42f3bce2025-02-03T05:50:52ZengWileyCase Reports in Cardiology2090-64042090-64122019-01-01201910.1155/2019/39372483937248Brugada Syndrome Caused by Autonomic Dysfunction in Multiple SclerosisMichel Ibrahim0Garly Saint-Croix1Rosario Colombo2Department of Internal Medicine, Jackson Memorial Hospital/University of Miami Hospital, Miami, FL, USADepartment of Internal Medicine, Jackson Memorial Hospital/University of Miami Hospital, Miami, FL, USADepartment of Cardiovascular Medicine, Jackson Memorial Hospital, Miami, FL, USAOnly one case report has previously described a patient with multiple sclerosis and a type 1 Brugada pattern on the electrocardiogram. Patients with multiple sclerosis have several neurological deficits including sensory symptoms, acute or subacute motor weakness, gait disturbance, and balance problems that may lead to an increased risk of falls. Concurrent autonomic dysfunction and neurologic consequences of multiple sclerosis may precipitate both mechanical falls and falls with loss of consciousness. While mechanistically different, the type 1 Brugada pattern presents similarly with syncope due to an insufficient cardiac output during dysrhythmia. In such patients, intracardiac defibrillators have shown to prevent sudden cardiac death in patients with the Brugada syndrome. In light of these similarly presenting but unique clinical entities, MS patients who develop a syncopal event in the setting of a spontaneous type I Brugada pattern pose a diagnostic and therapeutic dilemma. This case illustrates an approach to the risks and benefits of an ICD placement in an MS patient with the type 1 Brugada pattern.http://dx.doi.org/10.1155/2019/3937248 |
| spellingShingle | Michel Ibrahim Garly Saint-Croix Rosario Colombo Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis Case Reports in Cardiology |
| title | Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis |
| title_full | Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis |
| title_fullStr | Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis |
| title_full_unstemmed | Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis |
| title_short | Brugada Syndrome Caused by Autonomic Dysfunction in Multiple Sclerosis |
| title_sort | brugada syndrome caused by autonomic dysfunction in multiple sclerosis |
| url | http://dx.doi.org/10.1155/2019/3937248 |
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