Sustained intraocular pressure-lowering effect and biocompatibility of a single subconjunctival administration of hydrogel-encapsulated nano-brinzolamide

Abstract Brinzolamide is a widely used treatment for glaucoma, but its effectiveness relies on at least twice-daily dosing, which can be challenging for patient adherence. To overcome this limitation, we developed an injectable hydrogel-based delivery system designed to maintain therapeutic drug lev...

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Bibliographic Details
Main Authors: Jiahao Xu, Linyu Long, Xiaoyu Zhou, Xinyue Zhang, Li Liao, Dan Ji, Xuanchu Duan
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-025-06896-1
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