Transcriptomic and network toxicology approaches reveal potential mechanisms of DEHP induced intrahepatic cholestasis during pregnancy
Abstract The objective of this study was to investigate the hepatotoxic effects and molecular mechanisms underlying di(2-ethylhexyl) phthalate (DEHP)-induced intrahepatic cholestasis of pregnancy (ICP) through a network toxicology approach. Utilizing liver transcriptomics in conjunction with the Gen...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-05489-w |
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