Xanthogranulomatous pyelonephritis: presentation and management

Xanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipidladen foamy macrophages with both acute and chronic phase inflammatory cells. The aim of the study is to present our experience about patients with Xanthogranulomatous pyelonephritis. 29 patients were evaluated through...

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Main Authors: Răzvan C. Petca, Răzvan I. Popescu, Cristian Mareș, Claudia Mehedințu, Bogdan Mastalier, Dumitru C. Badiu, Nicoleta Măru, Vlad D. Constantin, Aida Petca
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Journal of Mind and Medical Sciences
Subjects:
Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1176&context=jmms
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author Răzvan C. Petca
Răzvan I. Popescu
Cristian Mareș
Claudia Mehedințu
Bogdan Mastalier
Dumitru C. Badiu
Nicoleta Măru
Vlad D. Constantin
Aida Petca
author_facet Răzvan C. Petca
Răzvan I. Popescu
Cristian Mareș
Claudia Mehedințu
Bogdan Mastalier
Dumitru C. Badiu
Nicoleta Măru
Vlad D. Constantin
Aida Petca
author_sort Răzvan C. Petca
collection DOAJ
description Xanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipidladen foamy macrophages with both acute and chronic phase inflammatory cells. The aim of the study is to present our experience about patients with Xanthogranulomatous pyelonephritis. 29 patients were evaluated through a complete anamnesis and the preoperative management included routine blood and biochemical tests, urine culture and renal ultrasound, intravenous urography and computed tomography (CT). All patients underwent open nephrectomy followed by the pathological exam. The main symptoms of these patients were fever and flank pain. Preoperative laboratory tests revealed anemia, leukocytosis and increasing levels of blood urea nitrogen (BUN) and creatinine. Kidney failure was noticed in almost half of the cases. This study succeeded to evaluate the demographic, clinical, biological, surgical and histological characteristics. A pathological diagnosis is mandatory mainly for the evaluation of its coexistence with renal carcinoma.
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issn 2392-7674
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publisher MDPI AG
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series Journal of Mind and Medical Sciences
spelling doaj-art-2e05bccca8ba4eadb3551fc47c009fb82025-08-20T03:18:27ZengMDPI AGJournal of Mind and Medical Sciences2392-76742019-05-016116917510.22543/7674.61.P169175Xanthogranulomatous pyelonephritis: presentation and managementRăzvan C. PetcaRăzvan I. PopescuCristian MareșClaudia MehedințuBogdan MastalierDumitru C. BadiuNicoleta MăruVlad D. ConstantinAida PetcaXanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipidladen foamy macrophages with both acute and chronic phase inflammatory cells. The aim of the study is to present our experience about patients with Xanthogranulomatous pyelonephritis. 29 patients were evaluated through a complete anamnesis and the preoperative management included routine blood and biochemical tests, urine culture and renal ultrasound, intravenous urography and computed tomography (CT). All patients underwent open nephrectomy followed by the pathological exam. The main symptoms of these patients were fever and flank pain. Preoperative laboratory tests revealed anemia, leukocytosis and increasing levels of blood urea nitrogen (BUN) and creatinine. Kidney failure was noticed in almost half of the cases. This study succeeded to evaluate the demographic, clinical, biological, surgical and histological characteristics. A pathological diagnosis is mandatory mainly for the evaluation of its coexistence with renal carcinoma.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1176&context=jmmsXanthogranulomatous pyelonephritisurinary tract infectionE. Colianemialeukocytosisnephrectomy
spellingShingle Răzvan C. Petca
Răzvan I. Popescu
Cristian Mareș
Claudia Mehedințu
Bogdan Mastalier
Dumitru C. Badiu
Nicoleta Măru
Vlad D. Constantin
Aida Petca
Xanthogranulomatous pyelonephritis: presentation and management
Journal of Mind and Medical Sciences
Xanthogranulomatous pyelonephritis
urinary tract infection
E. Coli
anemia
leukocytosis
nephrectomy
title Xanthogranulomatous pyelonephritis: presentation and management
title_full Xanthogranulomatous pyelonephritis: presentation and management
title_fullStr Xanthogranulomatous pyelonephritis: presentation and management
title_full_unstemmed Xanthogranulomatous pyelonephritis: presentation and management
title_short Xanthogranulomatous pyelonephritis: presentation and management
title_sort xanthogranulomatous pyelonephritis presentation and management
topic Xanthogranulomatous pyelonephritis
urinary tract infection
E. Coli
anemia
leukocytosis
nephrectomy
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1176&context=jmms
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