Endometrial stromal sarcoma: A review of the literature

Endometrial stromal sarcomas are rare malignant tumors of the uterus, and most of the information available in literature is based on small series or case reports. A proper preoperative diagnosis is difficult and in most cases the diagnosis is confirmed after hysterectomy for a presumed benign disea...

Full description

Saved in:
Bibliographic Details
Main Authors: Geetha Puliyath, M Krishnan Nair
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2012-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2012;volume=33;issue=1;spage=1;epage=6;aulast=Puliyath
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850198214252167168
author Geetha Puliyath
M Krishnan Nair
author_facet Geetha Puliyath
M Krishnan Nair
author_sort Geetha Puliyath
collection DOAJ
description Endometrial stromal sarcomas are rare malignant tumors of the uterus, and most of the information available in literature is based on small series or case reports. A proper preoperative diagnosis is difficult and in most cases the diagnosis is confirmed after hysterectomy for a presumed benign disease. Endometrial sampling, ultrasound, and magnetic resonance imaging can provide diagnostic clues. Total hysterectomy with bilateral salpingo-oopherectomy is the main line of management and for early disease complete cure is a reality. Ovarian conservation may be possible in young women with early stage disease and the role of lymphadenectomy is controversial. Adjuvant hormone therapy in the form of progesterone, gonadotropin releasing hormone analogues, and aromatase inhibitors are found to be effective in preventing recurrences. Hormone therapy, radiotherapy and surgical excision of the metastasis are recommended for recurrences.
format Article
id doaj-art-2e03b420d3fd4f74b6f8507cf8e149c7
institution OA Journals
issn 0971-5851
language English
publishDate 2012-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-2e03b420d3fd4f74b6f8507cf8e149c72025-08-20T02:12:55ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512012-01-013311610.4103/0971-5851.96960Endometrial stromal sarcoma: A review of the literatureGeetha PuliyathM Krishnan NairEndometrial stromal sarcomas are rare malignant tumors of the uterus, and most of the information available in literature is based on small series or case reports. A proper preoperative diagnosis is difficult and in most cases the diagnosis is confirmed after hysterectomy for a presumed benign disease. Endometrial sampling, ultrasound, and magnetic resonance imaging can provide diagnostic clues. Total hysterectomy with bilateral salpingo-oopherectomy is the main line of management and for early disease complete cure is a reality. Ovarian conservation may be possible in young women with early stage disease and the role of lymphadenectomy is controversial. Adjuvant hormone therapy in the form of progesterone, gonadotropin releasing hormone analogues, and aromatase inhibitors are found to be effective in preventing recurrences. Hormone therapy, radiotherapy and surgical excision of the metastasis are recommended for recurrences.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2012;volume=33;issue=1;spage=1;epage=6;aulast=PuliyathEndometrial stromal sarcomamalignant uterine tumoruterine sarcoma
spellingShingle Geetha Puliyath
M Krishnan Nair
Endometrial stromal sarcoma: A review of the literature
Indian Journal of Medical and Paediatric Oncology
Endometrial stromal sarcoma
malignant uterine tumor
uterine sarcoma
title Endometrial stromal sarcoma: A review of the literature
title_full Endometrial stromal sarcoma: A review of the literature
title_fullStr Endometrial stromal sarcoma: A review of the literature
title_full_unstemmed Endometrial stromal sarcoma: A review of the literature
title_short Endometrial stromal sarcoma: A review of the literature
title_sort endometrial stromal sarcoma a review of the literature
topic Endometrial stromal sarcoma
malignant uterine tumor
uterine sarcoma
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2012;volume=33;issue=1;spage=1;epage=6;aulast=Puliyath
work_keys_str_mv AT geethapuliyath endometrialstromalsarcomaareviewoftheliterature
AT mkrishnannair endometrialstromalsarcomaareviewoftheliterature