A novel mechanism of radiation-induced lung injury: METTL3 mediates fibrogenesis through N6-methyladenosine modification of YY1

A novel mechanism of radiation-induced lung injury: METTL3 mediates fibrogenesis through N6-methyladenosine modification of YY1

Abstract Background N6-methyladenosine (m6A) modification is implicated in various diseases pathogenesis and physiological processes. We investigated the regulatory function of METTL3, a central m6A methyltransferase, in mediating m6A modification of YY1. This study aims to delineate how m6A modific...

Full description

Saved in:
Bibliographic Details
Main Authors: Weiqiang Xu, Junxuan Yi, Xinfeng Wei, Mingwei Wang, Mingqi Zhao, Mengdie Zhao, Xinyan Wang, Yannan Shen, Zhicheng Wang, Shunzi Jin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06614-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items