New Insights into the Immunological Changes in IL-10-Deficient Mice during the Course of Spontaneous Inflammation in the Gut Mucosa
IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is illustrated by the fact that IL-10−/− mice develop spontaneous colitis. In this study, IL-10−/− mice were analyzed for immunological changes during colitis development. We found a reduced frequency of re...
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| Main Authors: | Ana Cristina Gomes-Santos, Thais Garcias Moreira, Archimedes Barbosa Castro-Junior, Bernardo Coelho Horta, Luisa Lemos, Deborah Nogueira Cruz, Mauro Andrade Freitas Guimarães, Denise Carmona Cara, Donna-Marie McCafferty, Ana Maria Caetano Faria |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/560817 |
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