Development of solid dispersion system from milk thistle dry extract by solvent method

Development of solid dispersion system from milk thistle dry extract by solvent method

Introduction. Silymarin is one of the main components used in preparations for hepatotropic therapy. Silymarin is contained in the dry extract of seeds and fruits of milk thistle (Silybum marianum L. Gaertn.), however it has poor bioavailability due to the crystalline state and low solubility of sil...

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Bibliographic Details
Main Authors: B. A. Perez, I. E. Kauhova, I. I. Terninko, O. N. Abrosimova, E. V. Vishnyakov, N. S. Pivovarova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-03-01
Series:Разработка и регистрация лекарственных средств
Subjects:
milk thistle dry extract
solid dispersion system
polymers
solvent method
Online Access:https://www.pharmjournal.ru/jour/article/view/2003
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