Platelet-bound C4d, low C3 and lupus anticoagulant associate with thrombosis in SLE

Platelet-bound C4d, low C3 and lupus anticoagulant associate with thrombosis in SLE

Background Low C3 and lupus anticoagulant (LAC) are known risk factors for thrombosis in SLE. We evaluated the association between C4d products deposited on platelets (PC4d) and thrombosis in SLE. Antiphosphatidyl serine/prothrombin (PS/PT) complex antibody was also evaluated as an alternative to LA...

Full description

Saved in:

Bibliographic Details
Main Authors:	John Conklin, Thierry Dervieux, Tyler O'Malley
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2019-12-01
Series:	Lupus Science and Medicine
Online Access:	https://lupus.bmj.com/content/6/1/e000318.full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Performance Characteristics of Different Anti-Double-Stranded DNA Antibody Assays in the Monitoring of Systemic Lupus Erythematosus
by: Michael Mahler, et al.
Published: (2017-01-01)

Cell-bound complement activation products associate with lupus severity in SLE
by: Richard A Furie, et al.
Published: (2020-10-01)

Randomised prospective trial to assess the clinical utility of multianalyte assay panel with complement activation products for the diagnosis of SLE
by: Daniel J Wallace, et al.
Published: (2019-12-01)

Management of childhood-onset systemic lupus erythematosus (cSLE) over the last two decades in Spain
by: Alina Boteanu, et al.
Published: (2025-05-01)

Accurate Laboratory Detection of Lupus Anticoagulant in Anticoagulated Patients: An Area for Adopting System based Collaboration in Thrombosis
by: Mona Alfaraj, et al.
Published: (2025-04-01)

Pathogenesis of Autoimmunity/Systemic Lupus Erythematosus (SLE)
by: Shunichi Shiozawa
Published: (2025-07-01)

Glucocorticoid tapering early in the course of juvenile SLE: association with lupus low disease activity state and outcomes
by: Seza Ozen, et al.
Published: (2025-05-01)

Anticoagulants in Pediatric Sinovenous Thrombosis
by: J Gordon Millichap
Published: (2010-06-01)

Sinovenous Thrombosis: Anticoagulation Therapy
by: J Gordon Millichap
Published: (1998-12-01)

Performance of the proposed ACR–EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms
by: Tom W J Huizinga, et al.
Published: (2019-06-01)

Clinical features of patients with systemic lupus erythematosus (SLE) attending the SLE outpatient clinic at Universitas Hospital in Bloemfontein, South Africa
by: Robyn Carey, et al.
Published: (2008-02-01)

Clinical outcomes of baricitinib in patients with systemic lupus erythematosus: Pooled analysis of SLE-BRAVE-I and SLE-BRAVE-II trials
by: Juntao Yin, et al.
Published: (2025-01-01)

Understanding the impact of delayed diagnosis and misdiagnosis of systemic lupus erythematosus (SLE)
by: Jordan L. Mitchell
Published: (2024-11-01)

WCN24-757 NEUROPSYCHIATRIC SLE (NPSLE) IN CHILDREN AND ADOLESCENTS WITH LUPUS NEPHRITIS
by: Eugene Yu Hin Chan, et al.
Published: (2024-04-01)

New representation of the non-symmetric homogeneous bounded domains in ℂ4 and ℂ5
by: Gr. Tsagas, et al.
Published: (1992-01-01)

Clinical Outcome of a Portosplenomesenteric Venous Thrombosis in Necrotizing Acute Pancreatitis with Protein C and S Deficiency Treated by Anticoagulation Therapy Alone
by: Firmin Ankouane, et al.
Published: (2015-01-01)

Conventional DCs from Male and Female Lupus-Prone B6.NZM Sle1/Sle2/Sle3 Mice Express an IFN Signature and Have a Higher Immunometabolism That Are Enhanced by Estrogen
by: Michael H. Lee, et al.
Published: (2018-01-01)

Anti-ribosomal-P protein antibodies and systemic lupus erythematosus (SLE): in a cross-sectional study of Danish adult patients with SLE, no significant association is found between anti-ribosomal-P and neuropsychiatric SLE
by: Anne Voss, et al.
Published: (2025-08-01)

Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE)
by: Evan Mulvihill, et al.
Published: (2019-12-01)

PREVENTION AND TREATMENT OF THROMBOSIS AND THROMBOEMBOLIAS WITH ORAL ANTICOAGULANTS
by: G. V. Arkadyeva
Published: (2003-12-01)

Association of Polymorphisms in C-Reactive Protein (CRP) Promoter -821 A>G, -390 C>A/T, and Plasma Interferon-α (IFN-α) with Plasma CRP Level in Javanese Systemic Lupus Erythematosus (SLE) Patients
by: Awalia Awalia, et al.
Published: (2021-10-01)

Systemic Lupus Erythematosus (SLE): A review on the prevalence, clinical manifestation, and disease assessment
by: Malarvili Selvaraja, et al.
Published: (2020-09-01)

SYSTEMIC LUPUS ERITHEMATOSUS (SLE): KELAINAN AUTOIMUN BAWAAN YANG LANGKA DAN MEKANISME BIOKIMIAWINYA
by: Evi Roviati
Published: (2012-04-01)

MONITORING OF ANTICOAGULANT THERAPY IN PATIENTS WITH DEEP VEIN THROMBOSIS
by: V. I. Petrov, et al.
Published: (2014-08-01)

Fungal microbiome in gut of systemic lupus erythematosus (SLE)-prone mice (pristane and FCGRIIb deficiency), a possible impact of fungi in lupus.
by: Thanya Cheibchalard, et al.
Published: (2024-01-01)

Escaping the catch 22 of lupus anticoagulant testing
by: Søren Andreas Just, et al.
Published: (2020-02-01)

Clinical correlations of serum anti-dsDNA immunoglobulin subfamilies in patients with systemic lupus erythematosus (SLE)
by: Jing Jing Wang, et al.
Published: (2025-12-01)

Fully-heavy hadronic molecules $$B_c^{(*)+} B_c^{(*)-}$$ B c ( ∗ ) + B c ( ∗ ) - bound by fully-heavy mesons
by: Wen-Ying Liu, et al.
Published: (2025-06-01)

Indirect anticoagulants for prevention and treatment of thrombosis and embolia in cardiovascular pathology
by: G. V. Arkadyeva, et al.
Published: (2007-06-01)

Progress on anticoagulation therapy and mechanical thrombectomy for cerebral venous thrombosis
by: LANG Ye, et al.
Published: (2025-06-01)

Correlation of Platelet to Lymphocyte Ratio and C-Reactive Protein to Albumin Ratio with MEX-SLEDAI Scores in Patients with Systemic Lupus Erythematosus
by: Rachel Amelia, et al.
Published: (2024-09-01)

Comparison of TLR4, NF-κB and IRF3 expression in kidney tissue between lupus nephritis (LN) and systemic lupus erythematosus (SLE): a pristane-induced lupus mice model study
by: Yuswanto Setyawan, et al.
Published: (2025-04-01)

Lupus anticoagulant: a clinical and laboratory diagnostic dilemma
by: Shalini Trivedi, et al.
Published: (2022-03-01)

Evaluation of different ways to identify persistent positivity of lupus anticoagulant in systemic lupus erythematosus
by: Laurence S Magder, et al.
Published: (2020-10-01)

Differences in gestational age at preterm birth can predict future cardiovascular events in systemic lupus erythematosus (SLE)
by: May Ching Soh, et al.
Published: (2025-06-01)

Risk factors for symptomatic Avascular Necrosis (AVN) in a multi-ethnic Systemic Lupus Erythematosus (SLE) cohort.
by: Syahrul Sazliyana Shaharir, et al.
Published: (2021-01-01)

Direct Oral Anticoagulants Versus Traditional Anticoagulation in Cirrhotic Patients with Portal Vein Thrombosis: Updated Systematic Review
by: Xiulin Xiao M.S., et al.
Published: (2024-11-01)

SLE: reconciling heterogeneity
by: Peter Izmirly, et al.
Published: (2019-12-01)

Cutaneous vasculitis in SLE
by: Romy Kallas
Published: (2020-10-01)

Effect of endovascular management and anticoagulation alone on acute deep venous thrombosis in patients with inferior vena cava thrombosis
by: Lei Sun, et al.
Published: (2025-07-01)