Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia
Megaloblastic anemia belongs to the subgroup of deficiency anemias. With the objective of describing the effect of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia, this research was carried out. Megaloblastic anemia occurs when the levels of folic acid (Vitamin B9) and cyanocob...
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| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2023-11-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/30535 |
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| author | Karen Aracelly Tobar Armendariz Silvia Tatiana Tite Andi |
| author_facet | Karen Aracelly Tobar Armendariz Silvia Tatiana Tite Andi |
| author_sort | Karen Aracelly Tobar Armendariz |
| collection | DOAJ |
| description | Megaloblastic anemia belongs to the subgroup of deficiency anemias. With the objective of describing the effect of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia, this research was carried out. Megaloblastic anemia occurs when the levels of folic acid (Vitamin B9) and cyanocobalamin (vitamin B12) are low, thus generating a decrease in the cellular capacity to synthesize deoxyribonucleic acid, which causes hematological alterations in all cell lines of the marrow bone (erythrocytes and platelets), mainly causing the generation of large red blood cells with low hemoglobin concentration. Vitamins B9 and B12 participate in the normal synthesis of nucleic acids, being directly involved in the synthesis of purines and pyrimidines, as well as cell maturation. The deficiency of these vitamins has an effect on the central nervous system functioning. |
| format | Article |
| id | doaj-art-2de1e66bb55f4f21ba429884db3d895b |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2023-11-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-2de1e66bb55f4f21ba429884db3d895b2025-01-30T21:29:02ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2023-11-01216133113372421Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemiaKaren Aracelly Tobar Armendariz0Silvia Tatiana Tite Andi1Universidad Regional Autónoma de los Andes. Ecuador.Universidad Regional Autónoma de los Andes. Ecuador.Megaloblastic anemia belongs to the subgroup of deficiency anemias. With the objective of describing the effect of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia, this research was carried out. Megaloblastic anemia occurs when the levels of folic acid (Vitamin B9) and cyanocobalamin (vitamin B12) are low, thus generating a decrease in the cellular capacity to synthesize deoxyribonucleic acid, which causes hematological alterations in all cell lines of the marrow bone (erythrocytes and platelets), mainly causing the generation of large red blood cells with low hemoglobin concentration. Vitamins B9 and B12 participate in the normal synthesis of nucleic acids, being directly involved in the synthesis of purines and pyrimidines, as well as cell maturation. The deficiency of these vitamins has an effect on the central nervous system functioning.http://medisur.sld.cu/index.php/medisur/article/view/30535anemia megaloblásticaácido fólicodeficiencia de vitamina b12 |
| spellingShingle | Karen Aracelly Tobar Armendariz Silvia Tatiana Tite Andi Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia Medisur anemia megaloblástica ácido fólico deficiencia de vitamina b12 |
| title | Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia |
| title_full | Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia |
| title_fullStr | Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia |
| title_full_unstemmed | Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia |
| title_short | Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia |
| title_sort | effects of b9 and b12 vitamins deficiency on the genesis of megaloblastic anemia |
| topic | anemia megaloblástica ácido fólico deficiencia de vitamina b12 |
| url | http://medisur.sld.cu/index.php/medisur/article/view/30535 |
| work_keys_str_mv | AT karenaracellytobararmendariz effectsofb9andb12vitaminsdeficiencyonthegenesisofmegaloblasticanemia AT silviatatianatiteandi effectsofb9andb12vitaminsdeficiencyonthegenesisofmegaloblasticanemia |