Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain

Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain

Low back pain (LBP) has long been the leading cause of worldwide productivity loss and the top cause of years lived with disability. Observational studies have reported associations between brain imaging-derived phenotypes (IDPs) and LBP; however, it is uncertain whether these relationships are caus...

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Bibliographic Details
Main Authors: Xiao-Yan Xie, Jian-Wei Lin, Jia-Yu Fang, Zhuo-Chen Chen, Peng-Cheng Li, Xiao-Yan Huang, Ming-Yan Guo, Li-Ling Lin, Ming-Hui Cao
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Brain Research Bulletin
Subjects:
Low back pain
Brain imaging-derived phenotypes
Causal effects
Mendelian randomization
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025002527
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