Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report

Abstract. Epignathus is an extremely rare congenital oropharyngeal teratoma. Here, we report a case of epignathus without intracranial extension in a fetus. The mass was first found by ultrasonography at 22 gestational weeks. Serial ultrasound examinations and magnetic resonance imaging confirmed th...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoyu Hu, Yijing Chu, Yunqing Chen, Min Zhao, Xiaofei Wang, Lin Xu, Dandan Shi
Format: Article
Language:English
Published: Wolters Kluwer Health 2023-04-01
Series:Maternal-Fetal Medicine
Online Access:http://journals.lww.com/10.1097/FM9.0000000000000116
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850142139483160576
author Xiaoyu Hu
Yijing Chu
Yunqing Chen
Min Zhao
Xiaofei Wang
Lin Xu
Dandan Shi
author_facet Xiaoyu Hu
Yijing Chu
Yunqing Chen
Min Zhao
Xiaofei Wang
Lin Xu
Dandan Shi
author_sort Xiaoyu Hu
collection DOAJ
description Abstract. Epignathus is an extremely rare congenital oropharyngeal teratoma. Here, we report a case of epignathus without intracranial extension in a fetus. The mass was first found by ultrasonography at 22 gestational weeks. Serial ultrasound examinations and magnetic resonance imaging confirmed that the fetus had neither central nervous system involvement nor abnormal nose or tooth. The baby was delivered at 37 weeks and six days of gestation via cesarean section set up for ex-utero intrapartum treatment. The postnatal pathologic examination confirmed the presence of mature tissues predominantly containing ectopic central nervous tissue, osseous tissue, and bronchial mucosal tissue. Most cases of epignathus are associated with malformation and death. Ultrasound and magnetic resonance imaging prenatal assessments are very important to facilitate counseling and understand prognosis. In conclusion, the ex-utero intrapartum treatment procedure is a good approach to improve the survival of infants with epignathus.
format Article
id doaj-art-2ddc815db77a4aadbe9060389065391b
institution OA Journals
issn 2096-6954
2641-5895
language English
publishDate 2023-04-01
publisher Wolters Kluwer Health
record_format Article
series Maternal-Fetal Medicine
spelling doaj-art-2ddc815db77a4aadbe9060389065391b2025-08-20T02:29:12ZengWolters Kluwer HealthMaternal-Fetal Medicine2096-69542641-58952023-04-015212312710.1097/FM9.0000000000000116202304000-00011Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case ReportXiaoyu Hu0Yijing Chu1Yunqing Chen2Min Zhao3Xiaofei Wang4Lin Xu5Dandan Shi1 Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China1 Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China2 Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.1 Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China1 Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China1 Department of Obstetrics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, ChinaAbstract. Epignathus is an extremely rare congenital oropharyngeal teratoma. Here, we report a case of epignathus without intracranial extension in a fetus. The mass was first found by ultrasonography at 22 gestational weeks. Serial ultrasound examinations and magnetic resonance imaging confirmed that the fetus had neither central nervous system involvement nor abnormal nose or tooth. The baby was delivered at 37 weeks and six days of gestation via cesarean section set up for ex-utero intrapartum treatment. The postnatal pathologic examination confirmed the presence of mature tissues predominantly containing ectopic central nervous tissue, osseous tissue, and bronchial mucosal tissue. Most cases of epignathus are associated with malformation and death. Ultrasound and magnetic resonance imaging prenatal assessments are very important to facilitate counseling and understand prognosis. In conclusion, the ex-utero intrapartum treatment procedure is a good approach to improve the survival of infants with epignathus.http://journals.lww.com/10.1097/FM9.0000000000000116
spellingShingle Xiaoyu Hu
Yijing Chu
Yunqing Chen
Min Zhao
Xiaofei Wang
Lin Xu
Dandan Shi
Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
Maternal-Fetal Medicine
title Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
title_full Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
title_fullStr Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
title_full_unstemmed Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
title_short Prenatal Diagnosis of a Giant Epignathus in the Second Trimester and Immediate Successful Management at Birth: A Case Report
title_sort prenatal diagnosis of a giant epignathus in the second trimester and immediate successful management at birth a case report
url http://journals.lww.com/10.1097/FM9.0000000000000116
work_keys_str_mv AT xiaoyuhu prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT yijingchu prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT yunqingchen prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT minzhao prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT xiaofeiwang prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT linxu prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport
AT dandanshi prenataldiagnosisofagiantepignathusinthesecondtrimesterandimmediatesuccessfulmanagementatbirthacasereport