Sex and gender differences in pain perception and management in clinical settings

Chronic pain, which is described as pain lasting for greater than 3 months, accounts for a large percentage of economic debt in the United States, with approximately 20% of Americans experiencing a form of chronic pain. Despite the current pharmacologic recommendations for pain treatment, there are...

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Main Authors: Jakara Morgan, Krystal Magwood, Joslyn Smith, Marjorie R. Jenkins, Alyson J. McGregor, Kelly M. Quesnelle
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:All Life
Subjects:
Online Access:http://dx.doi.org/10.1080/26895293.2024.2367421
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author Jakara Morgan
Krystal Magwood
Joslyn Smith
Marjorie R. Jenkins
Alyson J. McGregor
Kelly M. Quesnelle
author_facet Jakara Morgan
Krystal Magwood
Joslyn Smith
Marjorie R. Jenkins
Alyson J. McGregor
Kelly M. Quesnelle
author_sort Jakara Morgan
collection DOAJ
description Chronic pain, which is described as pain lasting for greater than 3 months, accounts for a large percentage of economic debt in the United States, with approximately 20% of Americans experiencing a form of chronic pain. Despite the current pharmacologic recommendations for pain treatment, there are differences in how medications are prescribed to patients. Gender and sex are common variables when discussing biases in both pain perception and treatment. Pain perception can differ amongst the sexes based on a myriad of reasons such as differences in gonadal hormones or chronic pain syndromes. The purpose of this narrative literature review is to report physiologic and pharmacokinetic differences between the sexes and highlight the possible biases in pain treatment amongst men and women. By bringing awareness to differences in pain perception and treatment experienced by men and women, clinically, we can increase the efficacy of pain management amongst the sexes.
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spelling doaj-art-2ddc66cf1b194849a1dcca3641a61b782025-01-20T14:38:00ZengTaylor & Francis GroupAll Life2689-53072024-12-01170110.1080/26895293.2024.23674212367421Sex and gender differences in pain perception and management in clinical settingsJakara Morgan0Krystal Magwood1Joslyn Smith2Marjorie R. Jenkins3Alyson J. McGregor4Kelly M. Quesnelle5University of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvilleChronic pain, which is described as pain lasting for greater than 3 months, accounts for a large percentage of economic debt in the United States, with approximately 20% of Americans experiencing a form of chronic pain. Despite the current pharmacologic recommendations for pain treatment, there are differences in how medications are prescribed to patients. Gender and sex are common variables when discussing biases in both pain perception and treatment. Pain perception can differ amongst the sexes based on a myriad of reasons such as differences in gonadal hormones or chronic pain syndromes. The purpose of this narrative literature review is to report physiologic and pharmacokinetic differences between the sexes and highlight the possible biases in pain treatment amongst men and women. By bringing awareness to differences in pain perception and treatment experienced by men and women, clinically, we can increase the efficacy of pain management amongst the sexes.http://dx.doi.org/10.1080/26895293.2024.2367421sex and genderpaindrugacute painchronic painpharmacokinetics
spellingShingle Jakara Morgan
Krystal Magwood
Joslyn Smith
Marjorie R. Jenkins
Alyson J. McGregor
Kelly M. Quesnelle
Sex and gender differences in pain perception and management in clinical settings
All Life
sex and gender
pain
drug
acute pain
chronic pain
pharmacokinetics
title Sex and gender differences in pain perception and management in clinical settings
title_full Sex and gender differences in pain perception and management in clinical settings
title_fullStr Sex and gender differences in pain perception and management in clinical settings
title_full_unstemmed Sex and gender differences in pain perception and management in clinical settings
title_short Sex and gender differences in pain perception and management in clinical settings
title_sort sex and gender differences in pain perception and management in clinical settings
topic sex and gender
pain
drug
acute pain
chronic pain
pharmacokinetics
url http://dx.doi.org/10.1080/26895293.2024.2367421
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AT marjorierjenkins sexandgenderdifferencesinpainperceptionandmanagementinclinicalsettings
AT alysonjmcgregor sexandgenderdifferencesinpainperceptionandmanagementinclinicalsettings
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