Serum metabolites characterize hepatic phenotypes and reveal shared pathways: results from population-based imaging

Serum metabolites characterize hepatic phenotypes and reveal shared pathways: results from population-based imaging

Abstract Background Steatotic liver disease is a major public health issue, with hepatic iron overload exacerbating fibrotic conditions. This study aimed to identify metabolites associated with hepatic fat and/or iron overload using targeted metabolomics in a population-based cohort. Methods We used...

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Bibliographic Details
Main Authors: Juliane Maushagen, Johanna Nattenmüller, Ricarda von Krüchten, Barbara Thorand, Annette Peters, Wolfgang Rathmann, Jerzy Adamski, Christopher L. Schlett, Fabian Bamberg, Rui Wang-Sattler, Susanne Rospleszcz
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Medicine
Subjects:
Steatotic liver disease
NAFLD
Liver fat
Liver iron
Metabolomics
Online Access:https://doi.org/10.1186/s10020-025-01309-z
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