Allosteric modulation of serotonin and dopamine transporters: New insights from computations and experiments
Human monoamine transporters (MATs) are critical to regulating monoaminergic neurotransmission by translocating their substrates from the synaptic space back into the presynaptic neurons. As such, their primary substrate binding site S1 has been targeted by a wide range of compounds for treating neu...
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| Main Authors: | Hoang Nguyen, Mary Hongying Cheng, Ji Young Lee, Shaili Aggarwal, Ole Valente Mortensen, Ivet Bahar |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
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| Series: | Current Research in Physiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665944124000099 |
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