Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice
<b><br> </b><br> S.V. Balalin<sup>1</sup>, V.P. Fokin<sup>1</sup>, O.V. Yuferov<sup>1</sup>, S.Z. Boskhomdzhieva<sup>2<br> </sup><br> <sup>1</sup> S. Fyodorov Eye Microsurgery Federal State Institutio...
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| Language: | Russian |
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Prime-Media
2019-01-01
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| Series: | РМЖ "Клиническая офтальмология" |
| Online Access: | http://clinopht.com/upload/iblock/bc3/bc3055369818715737ad35a87cfb5d07.pdf |
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| author | S.V. Balalin V.P. Fokin O.V. Yuferov S.Z. Boskhomdzhieva |
| author_facet | S.V. Balalin V.P. Fokin O.V. Yuferov S.Z. Boskhomdzhieva |
| author_sort | S.V. Balalin |
| collection | DOAJ |
| description | <b><br>
</b><br>
S.V. Balalin<sup>1</sup>, V.P. Fokin<sup>1</sup>, O.V. Yuferov<sup>1</sup>, S.Z. Boskhomdzhieva<sup>2<br>
</sup><br>
<sup>1</sup> S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, <br>
Russian Federation<br>
<sup>2</sup> Zhemchuev Republican Clinical Hospital, Elista, Russian Federation<br>
<br>
<b>Aim</b>: to determine tolerant IOP in patients with primary open-angle glaucoma (POAG) and to evaluate the effectiveness of drug therapy for glaucoma.<br>
<b>Patients and Methods:</b> tolerant IOP was determined using software and the effectiveness of drug treatment was analyzed in 341 patients with primary open-angle glaucoma (498 eyes). The average age of the patients was 69.5±0.39 years. Patients were divided into groups according to the level of IOP (P0, mm Hg), which was measured against the background of the initial drug therapy: with normal values of ophthalmotonous (fr om 11 to 21 mm Hg) — 69.7% (347 eyes), with moderately increased IOP values (fr om 22 to 32 mm Hg) — 26.5% (132 eyes) and high IOP values (over 32 mm Hg) — 3.8% (19 eyes). Prognosis of the progression rate of the glaucomatous process was estimated by the intolerance index (Iint).<br>
<b>Results</b>: the mean value of true IOP against the background of the initial drug therapy was 19.5±0.3 mm Hg, and the mean value of the tolerant pressure was 16.3±0.05 mm Hg, the difference between them was statistically significant (t=10.7; p=0.001). The mean value of the intolerance index was 3.1±0.27 mm Hg. Prognosis of the progression rate of glaucoma was detected in 164 eyes (32.9%), wh ere the intolerance index exceeded 4.7 mm Hg. Slow progression of the disease was found in 154 eyes (30.9%), wh ere the intolerance index ranged from 0.5 mm Hg to 4.7 mm Hg. Prognosis of stabilization of the glaucomatous process was determined in 180 eyes (36.1%).<br>
<b>Conclusions: </b>software application for the tolerant IOP determination in 36.9% of cases allowed to identify those needed to strengthen antihypertensive treatment among patients with POAG with normal ophthalmotonus values on the background of drug therapy and in 35,9% of cases to select patients for surgical treatment of glaucoma.<br>
<br>
<b>Key words:</b> open-angle glaucoma, individual and tolerant intraocular pressure, evaluation of the effectiveness of antihypertensive treatment.<br>
<b>For citation:</b> Balalin S.V., FokinV.P. , Yuferov O.V., Boskhomdzhieva S.Z. Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice. RMJ “Clinical ophthalmology”. 2018;4:199–202.<br> |
| format | Article |
| id | doaj-art-2dc57294661f4abca07bed0e8b80ca12 |
| institution | Kabale University |
| issn | 2311-7729 2619-1571 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | Prime-Media |
| record_format | Article |
| series | РМЖ "Клиническая офтальмология" |
| spelling | doaj-art-2dc57294661f4abca07bed0e8b80ca122025-01-16T09:39:39ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712019-01-0118430557Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practiceS.V. Balalin0V.P. Fokin1O.V. Yuferov2S.Z. Boskhomdzhieva3Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<b><br> </b><br> S.V. Balalin<sup>1</sup>, V.P. Fokin<sup>1</sup>, O.V. Yuferov<sup>1</sup>, S.Z. Boskhomdzhieva<sup>2<br> </sup><br> <sup>1</sup> S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, <br> Russian Federation<br> <sup>2</sup> Zhemchuev Republican Clinical Hospital, Elista, Russian Federation<br> <br> <b>Aim</b>: to determine tolerant IOP in patients with primary open-angle glaucoma (POAG) and to evaluate the effectiveness of drug therapy for glaucoma.<br> <b>Patients and Methods:</b> tolerant IOP was determined using software and the effectiveness of drug treatment was analyzed in 341 patients with primary open-angle glaucoma (498 eyes). The average age of the patients was 69.5±0.39 years. Patients were divided into groups according to the level of IOP (P0, mm Hg), which was measured against the background of the initial drug therapy: with normal values of ophthalmotonous (fr om 11 to 21 mm Hg) — 69.7% (347 eyes), with moderately increased IOP values (fr om 22 to 32 mm Hg) — 26.5% (132 eyes) and high IOP values (over 32 mm Hg) — 3.8% (19 eyes). Prognosis of the progression rate of the glaucomatous process was estimated by the intolerance index (Iint).<br> <b>Results</b>: the mean value of true IOP against the background of the initial drug therapy was 19.5±0.3 mm Hg, and the mean value of the tolerant pressure was 16.3±0.05 mm Hg, the difference between them was statistically significant (t=10.7; p=0.001). The mean value of the intolerance index was 3.1±0.27 mm Hg. Prognosis of the progression rate of glaucoma was detected in 164 eyes (32.9%), wh ere the intolerance index exceeded 4.7 mm Hg. Slow progression of the disease was found in 154 eyes (30.9%), wh ere the intolerance index ranged from 0.5 mm Hg to 4.7 mm Hg. Prognosis of stabilization of the glaucomatous process was determined in 180 eyes (36.1%).<br> <b>Conclusions: </b>software application for the tolerant IOP determination in 36.9% of cases allowed to identify those needed to strengthen antihypertensive treatment among patients with POAG with normal ophthalmotonus values on the background of drug therapy and in 35,9% of cases to select patients for surgical treatment of glaucoma.<br> <br> <b>Key words:</b> open-angle glaucoma, individual and tolerant intraocular pressure, evaluation of the effectiveness of antihypertensive treatment.<br> <b>For citation:</b> Balalin S.V., FokinV.P. , Yuferov O.V., Boskhomdzhieva S.Z. Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice. RMJ “Clinical ophthalmology”. 2018;4:199–202.<br>http://clinopht.com/upload/iblock/bc3/bc3055369818715737ad35a87cfb5d07.pdf |
| spellingShingle | S.V. Balalin V.P. Fokin O.V. Yuferov S.Z. Boskhomdzhieva Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice РМЖ "Клиническая офтальмология" |
| title | Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice |
| title_full | Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice |
| title_fullStr | Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice |
| title_full_unstemmed | Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice |
| title_short | Clinical significance of determining individual intraocular pressure in patients with primary open-angle glaucoma in ophthalmological practice |
| title_sort | clinical significance of determining individual intraocular pressure in patients with primary open angle glaucoma in ophthalmological practice |
| url | http://clinopht.com/upload/iblock/bc3/bc3055369818715737ad35a87cfb5d07.pdf |
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