Targeting the <i>ZMYM2-ANXA9</i> Axis with <i>FLT3</i> Inhibitor G749 Overcomes Oxaliplatin Resistance in Colorectal Cancer

Targeting the <i>ZMYM2-ANXA9</i> Axis with <i>FLT3</i> Inhibitor G749 Overcomes Oxaliplatin Resistance in Colorectal Cancer

<b>Background:</b> Chemoresistance and tumor recurrence remain major obstacles in colorectal cancer (CRC) therapy. Elucidating the molecular mechanisms underlying treatment resistance is critical for improving therapeutic outcomes. <b>Methods</b>: We analyzed transcriptomic p...

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Bibliographic Details
Main Authors: Dezheng Lin, Yucheng Xu, Huanmiao Zhan, Yufan Liang, Riyun Liu, Jun Liu, Dandong Luo, Xiaochuan Chen, Jiawei Cai, Yifeng Zou
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
<i>ANXA9</i>
<i>ZMYM2</i>
G749
colorectal cancer
chemoresistance
Online Access:https://www.mdpi.com/2227-9059/13/5/1247
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