Global aphasia as a predictor of mortality in the acute phase of a first stroke

OBJECTIVE: To establish whether vascular aphasic syndromes can predict stroke outcomes. METHOD: Thirty-seven adults were evaluated for speech and language within 72 hours after a single first-ever ischemic brain lesion, in blind association to CT and/or MR. RESULTS: Speech or language disabilities w...

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Main Authors: F F Oliveira, B P Damasceno
Format: Article
Language:English
Published: Thieme Revinter Publicações 2011-01-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300002&lng=en&tlng=en
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author F F Oliveira
B P Damasceno
author_facet F F Oliveira
B P Damasceno
author_sort F F Oliveira
collection DOAJ
description OBJECTIVE: To establish whether vascular aphasic syndromes can predict stroke outcomes. METHOD: Thirty-seven adults were evaluated for speech and language within 72 hours after a single first-ever ischemic brain lesion, in blind association to CT and/or MR. RESULTS: Speech or language disabilities were found in seven (87.5%) of the eight deceased patients and twenty-six (89.7%) of the twenty-nine survivors. Global aphasia was identified in eleven patients, all with left hemisphere lesions (nine mute; five deceased), consisting on a risk factor for death in the acute stroke phase (ρ=0.022). Age (z=1.65; ρ>0.09), thrombolysis (ρ=0.591), infarct size (ρ=0.076) and side (ρ=0.649) did not significantly influence survival. Absence of aphasia did not predict a better evolution, regardless of the affected hemisphere. Prevalence of cardiovascular risk factors was similar for all patient groups. CONCLUSION: Global aphasia in acute stroke can adversely affect prognosis, translated into impairment of dominant perisylvian vascular territories, with mutism as an important semiological element.
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spelling doaj-art-2db737476bf24d36a7cc2c81a0d9be202025-08-20T02:01:40ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272011-01-01692b27728210.1590/S0004-282X2011000300002S0004-282X2011000300002Global aphasia as a predictor of mortality in the acute phase of a first strokeF F Oliveira0B P Damasceno1Universidade Estadual de CampinasUniversidade Estadual de CampinasOBJECTIVE: To establish whether vascular aphasic syndromes can predict stroke outcomes. METHOD: Thirty-seven adults were evaluated for speech and language within 72 hours after a single first-ever ischemic brain lesion, in blind association to CT and/or MR. RESULTS: Speech or language disabilities were found in seven (87.5%) of the eight deceased patients and twenty-six (89.7%) of the twenty-nine survivors. Global aphasia was identified in eleven patients, all with left hemisphere lesions (nine mute; five deceased), consisting on a risk factor for death in the acute stroke phase (ρ=0.022). Age (z=1.65; ρ>0.09), thrombolysis (ρ=0.591), infarct size (ρ=0.076) and side (ρ=0.649) did not significantly influence survival. Absence of aphasia did not predict a better evolution, regardless of the affected hemisphere. Prevalence of cardiovascular risk factors was similar for all patient groups. CONCLUSION: Global aphasia in acute stroke can adversely affect prognosis, translated into impairment of dominant perisylvian vascular territories, with mutism as an important semiological element.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300002&lng=en&tlng=enlinguísticaafasiaacidente cerebral vascularinfarto encefálicolinguagemfalaavaliação da deficiênciaprognóstico
spellingShingle F F Oliveira
B P Damasceno
Global aphasia as a predictor of mortality in the acute phase of a first stroke
Arquivos de Neuro-Psiquiatria
linguística
afasia
acidente cerebral vascular
infarto encefálico
linguagem
fala
avaliação da deficiência
prognóstico
title Global aphasia as a predictor of mortality in the acute phase of a first stroke
title_full Global aphasia as a predictor of mortality in the acute phase of a first stroke
title_fullStr Global aphasia as a predictor of mortality in the acute phase of a first stroke
title_full_unstemmed Global aphasia as a predictor of mortality in the acute phase of a first stroke
title_short Global aphasia as a predictor of mortality in the acute phase of a first stroke
title_sort global aphasia as a predictor of mortality in the acute phase of a first stroke
topic linguística
afasia
acidente cerebral vascular
infarto encefálico
linguagem
fala
avaliação da deficiência
prognóstico
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300002&lng=en&tlng=en
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