Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations

Abstract Background This study investigated the treatment outcomes of ultrasound-guided sclerotherapy with pingyangmycin for periorbital lymphatic malformations (LMs). Method A retrospective study of patients with periorbital LMs who underwent ultrasound-guided sclerotherapy in our department betwee...

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Main Authors: Yixiao Li, Liang Wang, Dan Song, Bingxuan Jiao, Jing Li, Jie Zhou, Lei Guo
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-025-04154-0
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author Yixiao Li
Liang Wang
Dan Song
Bingxuan Jiao
Jing Li
Jie Zhou
Lei Guo
author_facet Yixiao Li
Liang Wang
Dan Song
Bingxuan Jiao
Jing Li
Jie Zhou
Lei Guo
author_sort Yixiao Li
collection DOAJ
description Abstract Background This study investigated the treatment outcomes of ultrasound-guided sclerotherapy with pingyangmycin for periorbital lymphatic malformations (LMs). Method A retrospective study of patients with periorbital LMs who underwent ultrasound-guided sclerotherapy in our department between 2017 and 2024 was conducted. Results One boy and seven girls with periorbital LMs were analyzed. Four cases had intraorbital lesions, two cases had lesions of the eyelids, and two cases had mixed lesions. Eight children underwent 13 sclerotherapy sessions, fluid was able to be withdrawn with a median amount of aspirate of 2 ml. After treatment, one of the eight children was lesion not seen on imaging, six showed strong improvement, and one showed weak improvement. None of the children experienced procedure-related adverse reactions. Conclusions Ultrasound-guided sclerotherapy is a treatment modality for periorbital LMs with good efficacy and few potential risks.
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publishDate 2025-05-01
publisher BMC
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series BMC Ophthalmology
spelling doaj-art-2db37dac5eac475890f36d86caa7b3b82025-08-20T02:39:07ZengBMCBMC Ophthalmology1471-24152025-05-012511510.1186/s12886-025-04154-0Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformationsYixiao Li0Liang Wang1Dan Song2Bingxuan Jiao3Jing Li4Jie Zhou5Lei Guo6Department of Cheeloo College of Medicine, Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong UniversityAbstract Background This study investigated the treatment outcomes of ultrasound-guided sclerotherapy with pingyangmycin for periorbital lymphatic malformations (LMs). Method A retrospective study of patients with periorbital LMs who underwent ultrasound-guided sclerotherapy in our department between 2017 and 2024 was conducted. Results One boy and seven girls with periorbital LMs were analyzed. Four cases had intraorbital lesions, two cases had lesions of the eyelids, and two cases had mixed lesions. Eight children underwent 13 sclerotherapy sessions, fluid was able to be withdrawn with a median amount of aspirate of 2 ml. After treatment, one of the eight children was lesion not seen on imaging, six showed strong improvement, and one showed weak improvement. None of the children experienced procedure-related adverse reactions. Conclusions Ultrasound-guided sclerotherapy is a treatment modality for periorbital LMs with good efficacy and few potential risks.https://doi.org/10.1186/s12886-025-04154-0Lymphatic malformationsPeriorbitalSclerotherapyUltrasound-guidedPingyangmycin
spellingShingle Yixiao Li
Liang Wang
Dan Song
Bingxuan Jiao
Jing Li
Jie Zhou
Lei Guo
Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
BMC Ophthalmology
Lymphatic malformations
Periorbital
Sclerotherapy
Ultrasound-guided
Pingyangmycin
title Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
title_full Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
title_fullStr Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
title_full_unstemmed Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
title_short Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
title_sort ultrasound guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations
topic Lymphatic malformations
Periorbital
Sclerotherapy
Ultrasound-guided
Pingyangmycin
url https://doi.org/10.1186/s12886-025-04154-0
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AT liangwang ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations
AT dansong ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations
AT bingxuanjiao ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations
AT jingli ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations
AT jiezhou ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations
AT leiguo ultrasoundguidedsclerotherapyofpingyangmycinforperiorbitallymphaticmalformations