New Paradigm in Treating Cancer: Right on Target
Cancer prevalence is increasing every year and now cancer is the third highest cause of death in developing countries. Effective anticancer treatment can prolong life and improve the patient’s quality of life. Targeted therapy is a new therapeutic modality which targets specific molecules in the can...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2016-09-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | https://actamedindones.org/index.php/ijim/article/view/153 |
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| _version_ | 1850067852375097344 |
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| author | Noorwati Sutandyo |
| author_facet | Noorwati Sutandyo |
| author_sort | Noorwati Sutandyo |
| collection | DOAJ |
| description | Cancer prevalence is increasing every year and now cancer is the third highest cause of death in developing countries. Effective anticancer treatment can prolong life and improve the patient’s quality of life. Targeted therapy is a new therapeutic modality which targets specific molecules in the cancer cell and disrupts dysregulated signaling pathways involved in carcinogenesis. Since targeted therapy does not attack normal cells, its side effects are considered low compared to chemotherapy. More than 15 drugs have been approved for treatment in various human cancers. These drugs can largely be grouped into tyrosine kinase inhibitors and monoclonal antibodies. This review will focus on the most common agents within both groups. |
| format | Article |
| id | doaj-art-2dae755a77fd440ba3ebccfcff7b5c6c |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2016-09-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-2dae755a77fd440ba3ebccfcff7b5c6c2025-08-20T02:48:12ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322016-09-01482New Paradigm in Treating Cancer: Right on TargetNoorwati Sutandyo0Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dharmais Cancer Center, Jakarta, IndonesiaCancer prevalence is increasing every year and now cancer is the third highest cause of death in developing countries. Effective anticancer treatment can prolong life and improve the patient’s quality of life. Targeted therapy is a new therapeutic modality which targets specific molecules in the cancer cell and disrupts dysregulated signaling pathways involved in carcinogenesis. Since targeted therapy does not attack normal cells, its side effects are considered low compared to chemotherapy. More than 15 drugs have been approved for treatment in various human cancers. These drugs can largely be grouped into tyrosine kinase inhibitors and monoclonal antibodies. This review will focus on the most common agents within both groups.https://actamedindones.org/index.php/ijim/article/view/153anticancer therapymonoclonal antibodiestargeted therapytyrosine kinase inhibitors |
| spellingShingle | Noorwati Sutandyo New Paradigm in Treating Cancer: Right on Target Acta Medica Indonesiana anticancer therapy monoclonal antibodies targeted therapy tyrosine kinase inhibitors |
| title | New Paradigm in Treating Cancer: Right on Target |
| title_full | New Paradigm in Treating Cancer: Right on Target |
| title_fullStr | New Paradigm in Treating Cancer: Right on Target |
| title_full_unstemmed | New Paradigm in Treating Cancer: Right on Target |
| title_short | New Paradigm in Treating Cancer: Right on Target |
| title_sort | new paradigm in treating cancer right on target |
| topic | anticancer therapy monoclonal antibodies targeted therapy tyrosine kinase inhibitors |
| url | https://actamedindones.org/index.php/ijim/article/view/153 |
| work_keys_str_mv | AT noorwatisutandyo newparadigmintreatingcancerrightontarget |