Oral mucosal changes caused by nicotine pouches: case series
Abstract Oral nicotine pouches are the latest products in the tobacco industry. They are manufactured by large tobacco companies and entice tobacco or nicotine addicts, although the products are presented as a ‘harmless choice.’ Nevertheless, dentists and oral health specialists worry about oral muc...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-09-01
|
| Series: | Diagnostic Pathology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13000-024-01549-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832572056722472960 |
|---|---|
| author | Sintija Miluna-Meldere Sarlote Agate Vanka Ingus Skadins Juta Kroica Maris Sperga Dagnija Rostoka |
| author_facet | Sintija Miluna-Meldere Sarlote Agate Vanka Ingus Skadins Juta Kroica Maris Sperga Dagnija Rostoka |
| author_sort | Sintija Miluna-Meldere |
| collection | DOAJ |
| description | Abstract Oral nicotine pouches are the latest products in the tobacco industry. They are manufactured by large tobacco companies and entice tobacco or nicotine addicts, although the products are presented as a ‘harmless choice.’ Nevertheless, dentists and oral health specialists worry about oral mucosal changes due to product interactions with the oral mucosa. Unfortunately, there are no case reports of oral mucosal changes from nicotine pouches that are also investigated histopathologically. The aim of the present study was to visually and histopathologically investigate oral mucosal changes in nicotine pouch users. An online retrospective survey regarding medical and dental health, dietary habits, and tobacco consumption habits was conducted (n = 50). Respondents were selected for further intraoral and histopathological investigation based on the inclusion criteria. All five respondents had oral lesions that were histopathologically analyzed. Visually, the lesions varied in form and intensity, but all appeared white at the location where the pouches were placed. Histopathological analyses revealed parakeratosis with acanthotic epithelium, intraepithelial and connective tissue oedema, and chronic inflammatory infiltration with lymphocytes and macrophages. Participants received information about nicotine cessation and oral health recommendations. In conclusion, nicotine pouches significantly impacted oral mucosa with white lesions that revealed important changes at the cellular level. |
| format | Article |
| id | doaj-art-2dadb67a3acc4177afc0062fd6612859 |
| institution | Kabale University |
| issn | 1746-1596 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Diagnostic Pathology |
| spelling | doaj-art-2dadb67a3acc4177afc0062fd66128592025-02-02T12:06:19ZengBMCDiagnostic Pathology1746-15962024-09-0119111010.1186/s13000-024-01549-3Oral mucosal changes caused by nicotine pouches: case seriesSintija Miluna-Meldere0Sarlote Agate Vanka1Ingus Skadins2Juta Kroica3Maris Sperga4Dagnija Rostoka5Department of Prosthetic Dentistry, Riga Stradins UniversityDepartment of Biology and Microbiology, Riga Stradins UniversityDepartment of Biology and Microbiology, Riga Stradins UniversityDepartment of Biology and Microbiology, Riga Stradins UniversityDepartment of Pathology, Riga Stradins UniversityDepartment of Biology and Microbiology, Riga Stradins UniversityAbstract Oral nicotine pouches are the latest products in the tobacco industry. They are manufactured by large tobacco companies and entice tobacco or nicotine addicts, although the products are presented as a ‘harmless choice.’ Nevertheless, dentists and oral health specialists worry about oral mucosal changes due to product interactions with the oral mucosa. Unfortunately, there are no case reports of oral mucosal changes from nicotine pouches that are also investigated histopathologically. The aim of the present study was to visually and histopathologically investigate oral mucosal changes in nicotine pouch users. An online retrospective survey regarding medical and dental health, dietary habits, and tobacco consumption habits was conducted (n = 50). Respondents were selected for further intraoral and histopathological investigation based on the inclusion criteria. All five respondents had oral lesions that were histopathologically analyzed. Visually, the lesions varied in form and intensity, but all appeared white at the location where the pouches were placed. Histopathological analyses revealed parakeratosis with acanthotic epithelium, intraepithelial and connective tissue oedema, and chronic inflammatory infiltration with lymphocytes and macrophages. Participants received information about nicotine cessation and oral health recommendations. In conclusion, nicotine pouches significantly impacted oral mucosa with white lesions that revealed important changes at the cellular level.https://doi.org/10.1186/s13000-024-01549-3Nicotine pouchesOral lesionsOral mucosaParakeratosis |
| spellingShingle | Sintija Miluna-Meldere Sarlote Agate Vanka Ingus Skadins Juta Kroica Maris Sperga Dagnija Rostoka Oral mucosal changes caused by nicotine pouches: case series Diagnostic Pathology Nicotine pouches Oral lesions Oral mucosa Parakeratosis |
| title | Oral mucosal changes caused by nicotine pouches: case series |
| title_full | Oral mucosal changes caused by nicotine pouches: case series |
| title_fullStr | Oral mucosal changes caused by nicotine pouches: case series |
| title_full_unstemmed | Oral mucosal changes caused by nicotine pouches: case series |
| title_short | Oral mucosal changes caused by nicotine pouches: case series |
| title_sort | oral mucosal changes caused by nicotine pouches case series |
| topic | Nicotine pouches Oral lesions Oral mucosa Parakeratosis |
| url | https://doi.org/10.1186/s13000-024-01549-3 |
| work_keys_str_mv | AT sintijamilunameldere oralmucosalchangescausedbynicotinepouchescaseseries AT sarloteagatevanka oralmucosalchangescausedbynicotinepouchescaseseries AT ingusskadins oralmucosalchangescausedbynicotinepouchescaseseries AT jutakroica oralmucosalchangescausedbynicotinepouchescaseseries AT marissperga oralmucosalchangescausedbynicotinepouchescaseseries AT dagnijarostoka oralmucosalchangescausedbynicotinepouchescaseseries |