Prognostic Models of Primary Sclerosing Cholangitis
Aim: to study the significance of prognostic scales in a target group of patients with primary sclerosing cholangitis (PSC) living in the Chelyabinsk region.Materials and methods. The study included 21 patients with a confirmed diagnosis of primary sclerosing cholangitis (PSC) and a disease duration...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2023-02-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/675 |
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| author | A. I. Dolgushina A. A. Selyanina V. V. Dubrovina G. A. Isyangildina E. R. Olevskaya |
| author_facet | A. I. Dolgushina A. A. Selyanina V. V. Dubrovina G. A. Isyangildina E. R. Olevskaya |
| author_sort | A. I. Dolgushina |
| collection | DOAJ |
| description | Aim: to study the significance of prognostic scales in a target group of patients with primary sclerosing cholangitis (PSC) living in the Chelyabinsk region.Materials and methods. The study included 21 patients with a confirmed diagnosis of primary sclerosing cholangitis (PSC) and a disease duration of at least two years. The primary endpoint studied was death. The MELD, Mayo Risk Score, Amsterdam-Oxford PSC Score, PREsTo score, and UK-PSC Score scales were calculated based on the medical records. Statistical processing was carried out using the SPSS Statistics v.22 application.Results. A retrospective assessment of the risk of mortality using the MELD, Mayo Risk Score and Amsterdam-Oxford PSC Score did not reveal a statistically significant difference between deceased and surviving patients. The UK-PSC Score scale showed the highest predictive value (p = 0.046).Conclusion. The new predictive model UK-PSC Score showed advantages in predicting death in PSC patients compared to other scales. |
| format | Article |
| id | doaj-art-2dad357d6f9c4fb58637301d37d56cfb |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2023-02-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-2dad357d6f9c4fb58637301d37d56cfb2025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732023-02-01325435010.22416/1382-4376-2022-32-5-43-50505Prognostic Models of Primary Sclerosing CholangitisA. I. Dolgushina0A. A. Selyanina1V. V. Dubrovina2G. A. Isyangildina3E. R. Olevskaya4South Ural State Medical UniversitySouth Ural State Medical UniversitySouth Ural State Medical UniversitySouth Ural State Medical UniversitySouth Ural State Medical University; Chelyabinsk Regional Clinical HospitalAim: to study the significance of prognostic scales in a target group of patients with primary sclerosing cholangitis (PSC) living in the Chelyabinsk region.Materials and methods. The study included 21 patients with a confirmed diagnosis of primary sclerosing cholangitis (PSC) and a disease duration of at least two years. The primary endpoint studied was death. The MELD, Mayo Risk Score, Amsterdam-Oxford PSC Score, PREsTo score, and UK-PSC Score scales were calculated based on the medical records. Statistical processing was carried out using the SPSS Statistics v.22 application.Results. A retrospective assessment of the risk of mortality using the MELD, Mayo Risk Score and Amsterdam-Oxford PSC Score did not reveal a statistically significant difference between deceased and surviving patients. The UK-PSC Score scale showed the highest predictive value (p = 0.046).Conclusion. The new predictive model UK-PSC Score showed advantages in predicting death in PSC patients compared to other scales.https://www.gastro-j.ru/jour/article/view/675primary sclerosing cholangitisnew prognostic modelsprognosissurvivalliver cirrhosis |
| spellingShingle | A. I. Dolgushina A. A. Selyanina V. V. Dubrovina G. A. Isyangildina E. R. Olevskaya Prognostic Models of Primary Sclerosing Cholangitis Российский журнал гастроэнтерологии, гепатологии, колопроктологии primary sclerosing cholangitis new prognostic models prognosis survival liver cirrhosis |
| title | Prognostic Models of Primary Sclerosing Cholangitis |
| title_full | Prognostic Models of Primary Sclerosing Cholangitis |
| title_fullStr | Prognostic Models of Primary Sclerosing Cholangitis |
| title_full_unstemmed | Prognostic Models of Primary Sclerosing Cholangitis |
| title_short | Prognostic Models of Primary Sclerosing Cholangitis |
| title_sort | prognostic models of primary sclerosing cholangitis |
| topic | primary sclerosing cholangitis new prognostic models prognosis survival liver cirrhosis |
| url | https://www.gastro-j.ru/jour/article/view/675 |
| work_keys_str_mv | AT aidolgushina prognosticmodelsofprimarysclerosingcholangitis AT aaselyanina prognosticmodelsofprimarysclerosingcholangitis AT vvdubrovina prognosticmodelsofprimarysclerosingcholangitis AT gaisyangildina prognosticmodelsofprimarysclerosingcholangitis AT erolevskaya prognosticmodelsofprimarysclerosingcholangitis |