Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature

Ameloblastoma is an epithelial odontogenic neoplasm with clinical and histological diversity. They are locally invasive tumors with 3 clinical variants such as solid, unicystic, and peripheral ameloblastomas, and the unicystic variant constitutes only 13%. Histologically, it shows diverse microscopi...

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Main Authors: Venkata Ramanand Oruganti, Shylaja Sanjeevareddygari, Manay Srinivas Munisekhar, Sharath Kumar Reddy Eppalapalli, Raghu Vamshi Vishwakarma, Kiran Kumar Ganji, Kiran R. Halkai, Rahul Halkai
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2021/2093927
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author Venkata Ramanand Oruganti
Shylaja Sanjeevareddygari
Manay Srinivas Munisekhar
Sharath Kumar Reddy Eppalapalli
Raghu Vamshi Vishwakarma
Kiran Kumar Ganji
Kiran R. Halkai
Rahul Halkai
author_facet Venkata Ramanand Oruganti
Shylaja Sanjeevareddygari
Manay Srinivas Munisekhar
Sharath Kumar Reddy Eppalapalli
Raghu Vamshi Vishwakarma
Kiran Kumar Ganji
Kiran R. Halkai
Rahul Halkai
author_sort Venkata Ramanand Oruganti
collection DOAJ
description Ameloblastoma is an epithelial odontogenic neoplasm with clinical and histological diversity. They are locally invasive tumors with 3 clinical variants such as solid, unicystic, and peripheral ameloblastomas, and the unicystic variant constitutes only 13%. Histologically, it shows diverse microscopic patterns that may occur isolated or in combination with other patterns. The granular cell variant accounts for 3.5% of all ameloblastoma cases. The eosinophilic granules seen in the cytoplasm of the tumor are thought to be lysosomes and presumably contribute to the pathogenesis of the tumor. Although such a phenomenon is rare in unicystic ameloblastoma, granular cell differentiation in solid multicystic ameloblastoma is a well-established phenomenon. In this paper, we present a unique case of unicystic ameloblastoma with granular cell differentiation with a brief review.
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institution OA Journals
issn 2090-6447
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publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-2dabfaa2047e48edabc7aa4b9cddd38a2025-08-20T02:24:07ZengWileyCase Reports in Dentistry2090-64472090-64552021-01-01202110.1155/2021/20939272093927Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of LiteratureVenkata Ramanand Oruganti0Shylaja Sanjeevareddygari1Manay Srinivas Munisekhar2Sharath Kumar Reddy Eppalapalli3Raghu Vamshi Vishwakarma4Kiran Kumar Ganji5Kiran R. Halkai6Rahul Halkai7Department of Oral Pathology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, IndiaDepartment of Oral Pathology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, IndiaOral Pathology Division, Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Al Jouf, Saudi ArabiaDepartment of Oral Pathology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, IndiaDepartment of Oral Pathology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, IndiaPeriodontics Division, Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Al Jouf, Saudi ArabiaDepartment of Conservative Dentistry and Endodontics, Al-Badar Dental College and Hospital, Kalaburgi, Karnataka, IndiaDepartment of Conservative Dentistry and Endodontics, Al-Badar Dental College and Hospital, Kalaburgi, Karnataka, IndiaAmeloblastoma is an epithelial odontogenic neoplasm with clinical and histological diversity. They are locally invasive tumors with 3 clinical variants such as solid, unicystic, and peripheral ameloblastomas, and the unicystic variant constitutes only 13%. Histologically, it shows diverse microscopic patterns that may occur isolated or in combination with other patterns. The granular cell variant accounts for 3.5% of all ameloblastoma cases. The eosinophilic granules seen in the cytoplasm of the tumor are thought to be lysosomes and presumably contribute to the pathogenesis of the tumor. Although such a phenomenon is rare in unicystic ameloblastoma, granular cell differentiation in solid multicystic ameloblastoma is a well-established phenomenon. In this paper, we present a unique case of unicystic ameloblastoma with granular cell differentiation with a brief review.http://dx.doi.org/10.1155/2021/2093927
spellingShingle Venkata Ramanand Oruganti
Shylaja Sanjeevareddygari
Manay Srinivas Munisekhar
Sharath Kumar Reddy Eppalapalli
Raghu Vamshi Vishwakarma
Kiran Kumar Ganji
Kiran R. Halkai
Rahul Halkai
Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
Case Reports in Dentistry
title Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
title_full Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
title_fullStr Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
title_full_unstemmed Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
title_short Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature
title_sort unusual variant of unicystic ameloblastoma with ceot like areas a rare case report with review of literature
url http://dx.doi.org/10.1155/2021/2093927
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