Developmental regulators in promoting genetic transformation efficiency in maize and other plants

Given global agricultural challenges such as population growth, climate change, and limitations on resources and the environment, as well as increasing diversity in breeding goals, relying on traditional breeding methods is inadequate to provide food security requirements and promote sustainable dev...

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Main Authors: Yilin Jiang, Xun Wei, Meirui Zhu, Xiaoyan Zhang, Qingping Jiang, ZiXiao Wang, Yanyong Cao, Xueli An, Xiangyuan Wan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Current Plant Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214662824000653
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author Yilin Jiang
Xun Wei
Meirui Zhu
Xiaoyan Zhang
Qingping Jiang
ZiXiao Wang
Yanyong Cao
Xueli An
Xiangyuan Wan
author_facet Yilin Jiang
Xun Wei
Meirui Zhu
Xiaoyan Zhang
Qingping Jiang
ZiXiao Wang
Yanyong Cao
Xueli An
Xiangyuan Wan
author_sort Yilin Jiang
collection DOAJ
description Given global agricultural challenges such as population growth, climate change, and limitations on resources and the environment, as well as increasing diversity in breeding goals, relying on traditional breeding methods is inadequate to provide food security requirements and promote sustainable development. Genetic transformation technology has become an effective tool for performing functional genomics research and molecular breeding. In this study, we conducted an in-depth analysis of 1669 literary works to investigate the potential of developmental regulators (DRs) in enhancing the efficiency of plant genetic transformation, with a concentration on their use in maize. Through multi-omics data analysis, we identified 12 homologous DRs from various species that are potentially applicable to maize. We identified a total of 41 possible disease resistances (DRs) for maize genetic transformation. Further experimental verification of ZmWIND1, a novel regulator belonging to the ERF/AP2 transcription factor (TF) family, showed that it significantly improved the efficiency of plant regeneration and transformation efficiency in maize. Specifically, compared to the control group, the callus induction rates for the pG3GB411-ZmWIND1 vector increased to 60.22 % and 47.85 % in Xiang249 and Zheng58, respectively. Transformation efficiency increased to 37.5 % in Xiang249 and 16.56 % in Zheng58, both significantly surpassing the control group. These findings have the potential to broaden the range of transformable maize varieties and lines, as well as introduce new genetic transformation methods in agricultural biotechnology, underscoring the immense potential to enhance genetic transformation efficiency through systematic exploration and application of DRs in maize.
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spelling doaj-art-2da45088e3cf41df9f4eb37886d9c03c2025-08-20T02:50:27ZengElsevierCurrent Plant Biology2214-66282024-12-014010038310.1016/j.cpb.2024.100383Developmental regulators in promoting genetic transformation efficiency in maize and other plantsYilin Jiang0Xun Wei1Meirui Zhu2Xiaoyan Zhang3Qingping Jiang4ZiXiao Wang5Yanyong Cao6Xueli An7Xiangyuan Wan8Research Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China; Beijing Engineering Laboratory of Main Crop Bio-Tech Breeding, Beijing International Science and Technology Cooperation Base of Bio-Tech Breeding, Zhongzhi International Institute of Agricultural Biosciences, Beijing 100192, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaInstitute of Cereal Crops, Henan Academy of Agricultural Sciences, Zhengzhou 450002, ChinaResearch Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China; Beijing Engineering Laboratory of Main Crop Bio-Tech Breeding, Beijing International Science and Technology Cooperation Base of Bio-Tech Breeding, Zhongzhi International Institute of Agricultural Biosciences, Beijing 100192, China; Corresponding authors at: Research Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.Research Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China; Beijing Engineering Laboratory of Main Crop Bio-Tech Breeding, Beijing International Science and Technology Cooperation Base of Bio-Tech Breeding, Zhongzhi International Institute of Agricultural Biosciences, Beijing 100192, China; Corresponding authors at: Research Institute of Biology and Agriculture, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.Given global agricultural challenges such as population growth, climate change, and limitations on resources and the environment, as well as increasing diversity in breeding goals, relying on traditional breeding methods is inadequate to provide food security requirements and promote sustainable development. Genetic transformation technology has become an effective tool for performing functional genomics research and molecular breeding. In this study, we conducted an in-depth analysis of 1669 literary works to investigate the potential of developmental regulators (DRs) in enhancing the efficiency of plant genetic transformation, with a concentration on their use in maize. Through multi-omics data analysis, we identified 12 homologous DRs from various species that are potentially applicable to maize. We identified a total of 41 possible disease resistances (DRs) for maize genetic transformation. Further experimental verification of ZmWIND1, a novel regulator belonging to the ERF/AP2 transcription factor (TF) family, showed that it significantly improved the efficiency of plant regeneration and transformation efficiency in maize. Specifically, compared to the control group, the callus induction rates for the pG3GB411-ZmWIND1 vector increased to 60.22 % and 47.85 % in Xiang249 and Zheng58, respectively. Transformation efficiency increased to 37.5 % in Xiang249 and 16.56 % in Zheng58, both significantly surpassing the control group. These findings have the potential to broaden the range of transformable maize varieties and lines, as well as introduce new genetic transformation methods in agricultural biotechnology, underscoring the immense potential to enhance genetic transformation efficiency through systematic exploration and application of DRs in maize.http://www.sciencedirect.com/science/article/pii/S2214662824000653MaizeMulti-omicsDevelopmental regulatorsZmWIND1Plant regenerationGenetic transformation
spellingShingle Yilin Jiang
Xun Wei
Meirui Zhu
Xiaoyan Zhang
Qingping Jiang
ZiXiao Wang
Yanyong Cao
Xueli An
Xiangyuan Wan
Developmental regulators in promoting genetic transformation efficiency in maize and other plants
Current Plant Biology
Maize
Multi-omics
Developmental regulators
ZmWIND1
Plant regeneration
Genetic transformation
title Developmental regulators in promoting genetic transformation efficiency in maize and other plants
title_full Developmental regulators in promoting genetic transformation efficiency in maize and other plants
title_fullStr Developmental regulators in promoting genetic transformation efficiency in maize and other plants
title_full_unstemmed Developmental regulators in promoting genetic transformation efficiency in maize and other plants
title_short Developmental regulators in promoting genetic transformation efficiency in maize and other plants
title_sort developmental regulators in promoting genetic transformation efficiency in maize and other plants
topic Maize
Multi-omics
Developmental regulators
ZmWIND1
Plant regeneration
Genetic transformation
url http://www.sciencedirect.com/science/article/pii/S2214662824000653
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