X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS

This review describes the recent advances in X-ray techniques, in particular dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT), for the imaging of postmenopausal osteoporosis. DXA is non-invasive, low-exposure, low-cost, and high-resolution...

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Main Authors: ALEXANDR S. Shkaraburov, GLEB I. Kolpinskiy, IGOR S. Zakharov, SERGEY P. Shkaraburov, VADIM G. Mozes
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2017-06-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/45
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author ALEXANDR S. Shkaraburov
GLEB I. Kolpinskiy
IGOR S. Zakharov
SERGEY P. Shkaraburov
VADIM G. Mozes
author_facet ALEXANDR S. Shkaraburov
GLEB I. Kolpinskiy
IGOR S. Zakharov
SERGEY P. Shkaraburov
VADIM G. Mozes
author_sort ALEXANDR S. Shkaraburov
collection DOAJ
description This review describes the recent advances in X-ray techniques, in particular dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT), for the imaging of postmenopausal osteoporosis. DXA is non-invasive, low-exposure, low-cost, and high-resolution method, therefore being widely applied for the measurement of bone mineral density. However, scoliosis, fractures, intervertebral disc calcification, and aortic calcification considerably reduce diagnostic accuracy of DXA. Another broadly used X-ray technique is QCT, which permits three-dimensional, separate imaging of cancellous and cortical bones. Alternatively, screening of peripheral osteoporosis can be performed employing quantitative ultrasound (QUS), which does not require exposure to ionizing radiation and expensive equipment but has lower sensitivity and specificity in detecting osteoporosis compared to DXA and QCT. Finally, we focus on radiopharmaceuticals as the promising agents for diagnosis of osteoporosis, despite high cost and low availability of the appropriate equipment limit their implementation.
format Article
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issn 2500-0764
2542-0941
language Russian
publishDate 2017-06-01
publisher Kemerovo State Medical University
record_format Article
series Фундаментальная и клиническая медицина
spelling doaj-art-2da126d198e14908838befc9270fda972025-08-20T03:19:11ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412017-06-0122707644X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSISALEXANDR S. Shkaraburov0GLEB I. Kolpinskiy1IGOR S. Zakharov2SERGEY P. Shkaraburov3VADIM G. Mozes4Kemerovo Clinical Diagnostic CenterKemerovo State Medical UniversityKemerovo State Medical UniversityKemerovo Regional Clinical HospitalKemerovo State Medical UniversityThis review describes the recent advances in X-ray techniques, in particular dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT), for the imaging of postmenopausal osteoporosis. DXA is non-invasive, low-exposure, low-cost, and high-resolution method, therefore being widely applied for the measurement of bone mineral density. However, scoliosis, fractures, intervertebral disc calcification, and aortic calcification considerably reduce diagnostic accuracy of DXA. Another broadly used X-ray technique is QCT, which permits three-dimensional, separate imaging of cancellous and cortical bones. Alternatively, screening of peripheral osteoporosis can be performed employing quantitative ultrasound (QUS), which does not require exposure to ionizing radiation and expensive equipment but has lower sensitivity and specificity in detecting osteoporosis compared to DXA and QCT. Finally, we focus on radiopharmaceuticals as the promising agents for diagnosis of osteoporosis, despite high cost and low availability of the appropriate equipment limit their implementation.https://fcm.kemsmu.ru/jour/article/view/45остеопорозминеральная плотность костикостная денситометрияosteoporosisbone mineral densitybone densitometry
spellingShingle ALEXANDR S. Shkaraburov
GLEB I. Kolpinskiy
IGOR S. Zakharov
SERGEY P. Shkaraburov
VADIM G. Mozes
X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
Фундаментальная и клиническая медицина
остеопороз
минеральная плотность кости
костная денситометрия
osteoporosis
bone mineral density
bone densitometry
title X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
title_full X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
title_fullStr X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
title_full_unstemmed X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
title_short X-RAY TECHNIQUES FOR DIAGNOSTICS OF POSTMENOPAUSAL OSTEOPOROSIS
title_sort x ray techniques for diagnostics of postmenopausal osteoporosis
topic остеопороз
минеральная плотность кости
костная денситометрия
osteoporosis
bone mineral density
bone densitometry
url https://fcm.kemsmu.ru/jour/article/view/45
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AT igorszakharov xraytechniquesfordiagnosticsofpostmenopausalosteoporosis
AT sergeypshkaraburov xraytechniquesfordiagnosticsofpostmenopausalosteoporosis
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