Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction
Aim. To evaluate efficiency of trimetazide MR combined with basic therapy of type 2 diabetes mellitus (DM2) in patients with myocardial infarction (MI). Materials and methods. The study included 106 patients with DM2 who underwent MI. Polycomponent basic therapy supplemented by trimetazideMR at a...
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| Language: | English |
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Endocrinology Research Centre
2009-06-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5400 |
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| author | E E Novitskaya G A Baryshnikova |
| author_facet | E E Novitskaya G A Baryshnikova |
| author_sort | E E Novitskaya |
| collection | DOAJ |
| description | Aim. To evaluate efficiency of trimetazide MR combined with basic therapy of type 2 diabetes mellitus (DM2) in patients with myocardial infarction (MI). Materials and methods. The study included 106 patients with DM2 who underwent MI. Polycomponent basic therapy supplemented by trimetazideMR at a daily dose of 70 mg was given to 51 patients. The patients condition 6 and 12 months after treatment was evaluated from the results of echo-CG, 24 hr ECG monitoring, and 6 min walking test. Quality of life was estimated using modified Minnesota questionnaire scores. Results. Trimetazide MR combined with polycomponent basic therapy reduced consumption of nitroglycerine by DM2 patients after myocardial infarction,frequency of ventricular and supraventricular extrasystole in 25.3 and 25.3% of the cases respectively. Episodes of painless myocardial ischemiaoccurred only in 35.6% of the patients. Long-term treatment with trimetazide MR as a component of combined therapy increased injectionfraction in patients with abnormal myocardial contractility (p |
| format | Article |
| id | doaj-art-2d9d731b1a17475d8bd36d66acd209a2 |
| institution | DOAJ |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2009-06-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-2d9d731b1a17475d8bd36d66acd209a22025-08-20T03:09:00ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782009-06-01122586110.14341/2072-0351-54005358Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarctionE E Novitskaya0G A Baryshnikova1ФГУ «Поликлиника №1» Управления делами Президента РФ, МоскваФГУ «Учебно-научный медицинский центр Управления делами Президента РФ», МоскваAim. To evaluate efficiency of trimetazide MR combined with basic therapy of type 2 diabetes mellitus (DM2) in patients with myocardial infarction (MI). Materials and methods. The study included 106 patients with DM2 who underwent MI. Polycomponent basic therapy supplemented by trimetazideMR at a daily dose of 70 mg was given to 51 patients. The patients condition 6 and 12 months after treatment was evaluated from the results of echo-CG, 24 hr ECG monitoring, and 6 min walking test. Quality of life was estimated using modified Minnesota questionnaire scores. Results. Trimetazide MR combined with polycomponent basic therapy reduced consumption of nitroglycerine by DM2 patients after myocardial infarction,frequency of ventricular and supraventricular extrasystole in 25.3 and 25.3% of the cases respectively. Episodes of painless myocardial ischemiaoccurred only in 35.6% of the patients. Long-term treatment with trimetazide MR as a component of combined therapy increased injectionfraction in patients with abnormal myocardial contractility (phttps://www.dia-endojournals.ru/jour/article/view/5400diabetes mellituscoronary heart diseasetrimetazide mrmyocardial infarction |
| spellingShingle | E E Novitskaya G A Baryshnikova Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction Сахарный диабет diabetes mellitus coronary heart disease trimetazide mr myocardial infarction |
| title | Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction |
| title_full | Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction |
| title_fullStr | Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction |
| title_full_unstemmed | Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction |
| title_short | Therapeutic efficiency of trimetazide MR in patients with type 2 diabetes mellitus after myocardial infarction |
| title_sort | therapeutic efficiency of trimetazide mr in patients with type 2 diabetes mellitus after myocardial infarction |
| topic | diabetes mellitus coronary heart disease trimetazide mr myocardial infarction |
| url | https://www.dia-endojournals.ru/jour/article/view/5400 |
| work_keys_str_mv | AT eenovitskaya therapeuticefficiencyoftrimetazidemrinpatientswithtype2diabetesmellitusaftermyocardialinfarction AT gabaryshnikova therapeuticefficiencyoftrimetazidemrinpatientswithtype2diabetesmellitusaftermyocardialinfarction |