The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia

The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia

Abstract Background The two subtypes of primary progressive aphasia (PPA) associated with Frontotemporal Lobar Degeneration (FTLD)—non-fluent (nfvPPA) and semantic (svPPA)—have distinct structural and functional abnormalities. Transcranial direct current stimulation (tDCS) targets the language netwo...

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Main Authors: Sagarika Bhattacharjee, P. T. Sivakumar, Ganesan Venkatasubramanian, Kenichi Oishi, Kyrana Tsapkini, S. H. Annabel Chen, Brenda Rapp, John E. Desmond, T. N. Sathyaprabha, Kaviraja Udupa, Rajan Kashyap
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Pathology
Specific tDCS, Primary progressive aphasia
Semantic and non
Fluent, structural atrophy, functional entropy, current
Atrophy
Entropy relationship
Online Access:https://doi.org/10.1186/s13195-025-01737-3
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