The effect of a systematic multi-dimensional assessment in severe uncontrolled asthma: a literature review and protocol for an investigator-initiated, open-label, randomized-controlled trial (EXACT@home study)

Abstract Introduction Severe asthma affects 3.6% of the asthma population, in which patients are uncontrolled despite optimal drug therapy and management of treatable traits. These patients are eligible for treatment with biologicals, which provide significant benefits but are costly and need precis...

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Main Authors:	L. Bult, G. J. Braunstahl, J. G. J. V. Aerts, D. Bänffer, J. S. J. A. van Campen, M. S. van Daalen, Y. van Dooren, U. Flanders, E. S. Geurts, P. P. Hekking, R. Heller - Baan, M. J. A. Jans, J. H. Kappen, R. C. A. Mies, B. Oppedijk, M. de la Roij - Hartmans, S. Van der Sar - Van der Brugge, Y. Türk, E. Vis, R. Wolters, E. C. Vasbinder, J. C. C. M. in ‘t Veen
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Series:	BMC Pulmonary Medicine
Subjects:	Systematic assessment Treatable traits Difficult-to-treat asthma Severe asthma EHealth
Online Access:	https://doi.org/10.1186/s12890-025-03646-5
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The effect of a systematic multi-dimensional assessment in severe uncontrolled asthma: a literature review and protocol for an investigator-initiated, open-label, randomized-controlled trial (EXACT@home study)

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