Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report
In this preliminary report the results of PCR for detection of DNA sequences (65 KDa antigen) of Mycobacterium tuberculosis in CSF samples from 20 patients are registered. In 10 patients there were clinical and laboratory findings suggesting the diagnosis of tuberculous meningitis (test group). In t...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1994-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000300029&lng=en&tlng=en |
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| _version_ | 1850236963308699648 |
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| author | L.R. Machado J.A. Livramento S.P. Bydlowski I. Bendit L.M. Bravo A. Spina-frança |
| author_facet | L.R. Machado J.A. Livramento S.P. Bydlowski I. Bendit L.M. Bravo A. Spina-frança |
| author_sort | L.R. Machado |
| collection | DOAJ |
| description | In this preliminary report the results of PCR for detection of DNA sequences (65 KDa antigen) of Mycobacterium tuberculosis in CSF samples from 20 patients are registered. In 10 patients there were clinical and laboratory findings suggesting the diagnosis of tuberculous meningitis (test group). In the other 10 patients, clinical and laboratory findings suggested meningitis or meningo-encephalitis from other etiologies (control group). In 7 patients from the test group antigenic DNA sequences of Mycobacterium tuberculosis were found in CSF by PCR; positive results were not registered in the control group. |
| format | Article |
| id | doaj-art-2d7e5a114e2c46a3aee1a4f6fb0e45c3 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 1994-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-2d7e5a114e2c46a3aee1a4f6fb0e45c32025-08-20T02:01:51ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271994-09-0152344544610.1590/S0004-282X1994000300029S0004-282X1994000300029Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary reportL.R. Machado0J.A. Livramento1S.P. Bydlowski2I. Bendit3L.M. Bravo4A. Spina-frança5Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloIn this preliminary report the results of PCR for detection of DNA sequences (65 KDa antigen) of Mycobacterium tuberculosis in CSF samples from 20 patients are registered. In 10 patients there were clinical and laboratory findings suggesting the diagnosis of tuberculous meningitis (test group). In the other 10 patients, clinical and laboratory findings suggested meningitis or meningo-encephalitis from other etiologies (control group). In 7 patients from the test group antigenic DNA sequences of Mycobacterium tuberculosis were found in CSF by PCR; positive results were not registered in the control group.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000300029&lng=en&tlng=enPCRLCRmeningoencefalite tuberculosameningoencefalites |
| spellingShingle | L.R. Machado J.A. Livramento S.P. Bydlowski I. Bendit L.M. Bravo A. Spina-frança Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report Arquivos de Neuro-Psiquiatria PCR LCR meningoencefalite tuberculosa meningoencefalites |
| title | Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report |
| title_full | Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report |
| title_fullStr | Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report |
| title_full_unstemmed | Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report |
| title_short | Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report |
| title_sort | polymerase chain reaction in the diagnosis of tuberculous meningitis preliminary report |
| topic | PCR LCR meningoencefalite tuberculosa meningoencefalites |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000300029&lng=en&tlng=en |
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