A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy

Acute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 wee...

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Main Authors: Tomomi Hara, Haruhiko Kanasaki, Aki Oride, Tomoko Ishihara, Satoru Kyo
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2015/469527
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author Tomomi Hara
Haruhiko Kanasaki
Aki Oride
Tomoko Ishihara
Satoru Kyo
author_facet Tomomi Hara
Haruhiko Kanasaki
Aki Oride
Tomoko Ishihara
Satoru Kyo
author_sort Tomomi Hara
collection DOAJ
description Acute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 weeks of gestation complained of severe lower abdominal pain. The pain gradually worsened and migrated toward the epigastric region. She had no history of chronic alcoholism. Blood investigations showed elevated level of C-reactive protein (9.58 mg/dL), pancreatic amylase (170 IU/L), and lipase (332 IU/L). There was no gallstone and no abnormality in the pancreatic and biliary ducts on ultrasonography. Antinuclear antibody and IgG4 were negative and no evidence of hyperlipidemia or diabetes was found. There was also no evidence of viral infection. On the third day of hospitalization, she was diagnosed with severe acute pancreatitis on magnetic resonance imaging. Medical interventions were initiated with nafamostat mesilate and ulinastatin, and parenteral nutrition was administered through a central venous catheter. On the eighth day of hospitalization, her condition gradually improved with a decreased level of pancreatic amylase and the pain subsided. After conservative management, she did not have any recurrence during her pregnancy.
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spelling doaj-art-2d7b0f1ab03d4785aad8e9f7ea42f8ad2025-02-03T07:25:17ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/469527469527A Case of Idiopathic Acute Pancreatitis in the First Trimester of PregnancyTomomi Hara0Haruhiko Kanasaki1Aki Oride2Tomoko Ishihara3Satoru Kyo4Department of Obstetrics and Gynecology, Shimane University School of Medicine, Izumo, Shimane 693-8501, JapanDepartment of Obstetrics and Gynecology, Shimane University School of Medicine, Izumo, Shimane 693-8501, JapanDepartment of Obstetrics and Gynecology, Shimane University School of Medicine, Izumo, Shimane 693-8501, JapanDepartment of Obstetrics and Gynecology, Shimane University School of Medicine, Izumo, Shimane 693-8501, JapanDepartment of Obstetrics and Gynecology, Shimane University School of Medicine, Izumo, Shimane 693-8501, JapanAcute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 weeks of gestation complained of severe lower abdominal pain. The pain gradually worsened and migrated toward the epigastric region. She had no history of chronic alcoholism. Blood investigations showed elevated level of C-reactive protein (9.58 mg/dL), pancreatic amylase (170 IU/L), and lipase (332 IU/L). There was no gallstone and no abnormality in the pancreatic and biliary ducts on ultrasonography. Antinuclear antibody and IgG4 were negative and no evidence of hyperlipidemia or diabetes was found. There was also no evidence of viral infection. On the third day of hospitalization, she was diagnosed with severe acute pancreatitis on magnetic resonance imaging. Medical interventions were initiated with nafamostat mesilate and ulinastatin, and parenteral nutrition was administered through a central venous catheter. On the eighth day of hospitalization, her condition gradually improved with a decreased level of pancreatic amylase and the pain subsided. After conservative management, she did not have any recurrence during her pregnancy.http://dx.doi.org/10.1155/2015/469527
spellingShingle Tomomi Hara
Haruhiko Kanasaki
Aki Oride
Tomoko Ishihara
Satoru Kyo
A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
Case Reports in Obstetrics and Gynecology
title A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_full A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_fullStr A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_full_unstemmed A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_short A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_sort case of idiopathic acute pancreatitis in the first trimester of pregnancy
url http://dx.doi.org/10.1155/2015/469527
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