Bacteroides expand the functional versatility of a conserved transcription factor and transcribed DNA to program capsule diversity

Bacteroides expand the functional versatility of a conserved transcription factor and transcribed DNA to program capsule diversity

Abstract The genomes of human gut bacteria in the genus Bacteroides include numerous operons for biosynthesis of diverse capsular polysaccharides (CPSs). The first two genes of each CPS operon encode a locus-specific paralog of transcription elongation factor NusG (called UpxY), which enhances trans...

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Bibliographic Details
Main Authors: Jason Saba, Katia Flores, Bailey Marshall, Michael D. Engstrom, Yikai Peng, Atharv S. Garje, Laurie E. Comstock, Robert Landick
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55215-9
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