Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery
This study was designed to evaluate the effect of major surgery on thyroid hormones and thyrotropin in patient undergoing major lower abdominal surgery. The study included fifty patients scheduled for elective major lower abdominal surgery, the serum levels of T3, T4 and TSH were determined one day...
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| Format: | Article |
| Language: | English |
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University of Baghdad, College of Science for Women
2014-12-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2050 |
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| author | Baghdad Science Journal |
| author_facet | Baghdad Science Journal |
| author_sort | Baghdad Science Journal |
| collection | DOAJ |
| description | This study was designed to evaluate the effect of major surgery on thyroid hormones and thyrotropin in patient undergoing major lower abdominal surgery. The study included fifty patients scheduled for elective major lower abdominal surgery, the serum levels of T3, T4 and TSH were determined one day preoperatively, intraoperative, one day postoperatively, two days postoperatively, and rT3 was determined one day preoperatively, and one day postoperatively. We observed that the levels of (T3, T4, TSH) increased significantly (P0.05). rT3 increased not significant (P>0.05) in one day postoperatively. It has been proposed these changes due to surgical stress that inhibits peripheral conversion of T4 to T3 by inhibiting peripheral 5'-deiodinase activity, also The absence of pituitary response to changes in serum levels of T3 and T4.According to the results of this study there is a transient abnormality in thyroid function tests in patient undergoing elective major surgery and this abnormality due to surgical stress. |
| format | Article |
| id | doaj-art-2d7275a524484ffc80859bca4192a85e |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-2d7275a524484ffc80859bca4192a85e2025-08-20T03:58:07ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862014-12-0111410.21123/bsj.11.4.1542-1548Study the Changes of Thyroid Hormones Levels Following Major Urological SurgeryBaghdad Science JournalThis study was designed to evaluate the effect of major surgery on thyroid hormones and thyrotropin in patient undergoing major lower abdominal surgery. The study included fifty patients scheduled for elective major lower abdominal surgery, the serum levels of T3, T4 and TSH were determined one day preoperatively, intraoperative, one day postoperatively, two days postoperatively, and rT3 was determined one day preoperatively, and one day postoperatively. We observed that the levels of (T3, T4, TSH) increased significantly (P0.05). rT3 increased not significant (P>0.05) in one day postoperatively. It has been proposed these changes due to surgical stress that inhibits peripheral conversion of T4 to T3 by inhibiting peripheral 5'-deiodinase activity, also The absence of pituitary response to changes in serum levels of T3 and T4.According to the results of this study there is a transient abnormality in thyroid function tests in patient undergoing elective major surgery and this abnormality due to surgical stress.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2050Major surgery, Thyroid hormones, Thyrotropin hormone |
| spellingShingle | Baghdad Science Journal Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery مجلة بغداد للعلوم Major surgery, Thyroid hormones, Thyrotropin hormone |
| title | Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery |
| title_full | Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery |
| title_fullStr | Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery |
| title_full_unstemmed | Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery |
| title_short | Study the Changes of Thyroid Hormones Levels Following Major Urological Surgery |
| title_sort | study the changes of thyroid hormones levels following major urological surgery |
| topic | Major surgery, Thyroid hormones, Thyrotropin hormone |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2050 |
| work_keys_str_mv | AT baghdadsciencejournal studythechangesofthyroidhormoneslevelsfollowingmajorurologicalsurgery |