Large animal models in gynecology: status and future perspectives
The purpose of this review is to evaluate the effectiveness of large animal models in gynecology research and provide future perspectives. Gynecological diseases are diverse and pose a serious threat to women’s physical and mental health. In addition to the commonly used small animal models, large a...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2025.1588098/full |
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| author | Dan Zhao Xue Li Xu Zheng Xiangrui Xie Yanan Zhao Yang Liu |
| author_facet | Dan Zhao Xue Li Xu Zheng Xiangrui Xie Yanan Zhao Yang Liu |
| author_sort | Dan Zhao |
| collection | DOAJ |
| description | The purpose of this review is to evaluate the effectiveness of large animal models in gynecology research and provide future perspectives. Gynecological diseases are diverse and pose a serious threat to women’s physical and mental health. In addition to the commonly used small animal models, large animal models have gradually entered the field of gynecological research. Results suggest that large animal models offer significant advantages in simulating human physiological processes, despite ethical and practical challenges. This paper reviews the application of large animal models in the study of gynecological diseases, provides a summary of the research characteristics of large animal models, analyses the advantages and challenges of these models in disease research, and compares the research differences between large and small animal models. It also discusses the relationship between these models and new alternative models, with a view to providing more new ideas for the selection of animal models in the study of gynecological diseases. |
| format | Article |
| id | doaj-art-2d6baa674b4d4ae5a7b0df4bfbccc77f |
| institution | Kabale University |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-2d6baa674b4d4ae5a7b0df4bfbccc77f2025-08-20T03:52:38ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-05-011210.3389/fvets.2025.15880981588098Large animal models in gynecology: status and future perspectivesDan Zhao0Xue Li1Xu Zheng2Xiangrui Xie3Yanan Zhao4Yang Liu5College of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartment of Gynecology, The Third Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, ChinaDepartment of Tuina, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, ChinaCollege of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, Jilin, ChinaInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, ChinaDepartment of Acupuncture, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, ChinaThe purpose of this review is to evaluate the effectiveness of large animal models in gynecology research and provide future perspectives. Gynecological diseases are diverse and pose a serious threat to women’s physical and mental health. In addition to the commonly used small animal models, large animal models have gradually entered the field of gynecological research. Results suggest that large animal models offer significant advantages in simulating human physiological processes, despite ethical and practical challenges. This paper reviews the application of large animal models in the study of gynecological diseases, provides a summary of the research characteristics of large animal models, analyses the advantages and challenges of these models in disease research, and compares the research differences between large and small animal models. It also discusses the relationship between these models and new alternative models, with a view to providing more new ideas for the selection of animal models in the study of gynecological diseases.https://www.frontiersin.org/articles/10.3389/fvets.2025.1588098/fulllarge animal modelsgynecological diseasesnon-human primatespigssheep |
| spellingShingle | Dan Zhao Xue Li Xu Zheng Xiangrui Xie Yanan Zhao Yang Liu Large animal models in gynecology: status and future perspectives Frontiers in Veterinary Science large animal models gynecological diseases non-human primates pigs sheep |
| title | Large animal models in gynecology: status and future perspectives |
| title_full | Large animal models in gynecology: status and future perspectives |
| title_fullStr | Large animal models in gynecology: status and future perspectives |
| title_full_unstemmed | Large animal models in gynecology: status and future perspectives |
| title_short | Large animal models in gynecology: status and future perspectives |
| title_sort | large animal models in gynecology status and future perspectives |
| topic | large animal models gynecological diseases non-human primates pigs sheep |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2025.1588098/full |
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