New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions
In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give th...
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| Format: | Article |
| Language: | English |
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University of Tehran
2015-12-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
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| Online Access: | https://jsciences.ut.ac.ir/article_56000_a43391af6fd2ff68d1ec23ee2aac7acd.pdf |
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| _version_ | 1849309574693126144 |
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| author | B. Mirza M. H. Sayahi |
| author_facet | B. Mirza M. H. Sayahi |
| author_sort | B. Mirza |
| collection | DOAJ |
| description | In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give the corresponding products. All compounds showed moderate activities comparing with staurosporine as the reference drug. |
| format | Article |
| id | doaj-art-2d661726cc3b43a89f05b20bfe89cc97 |
| institution | Kabale University |
| issn | 1016-1104 2345-6914 |
| language | English |
| publishDate | 2015-12-01 |
| publisher | University of Tehran |
| record_format | Article |
| series | Journal of Sciences, Islamic Republic of Iran |
| spelling | doaj-art-2d661726cc3b43a89f05b20bfe89cc972025-08-20T03:54:07ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69142015-12-0126432132556000New Homogeneous And Robust Catalyst for Heck and Suzuki ReactionsB. Mirza0M. H. Sayahi12 Department of Applied Chemistry, Faculty of science, Islamic Azad University, Tehran, Islamic Republic of Iran1 Department of Chemistry, Payame Noor Universtiy (PNU), P.O. Box 19395-3697, Tehran, Islamic Republic of IranIn this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give the corresponding products. All compounds showed moderate activities comparing with staurosporine as the reference drug.https://jsciences.ut.ac.ir/article_56000_a43391af6fd2ff68d1ec23ee2aac7acd.pdfethyl 2,4-dioxo-4-arylbutanoatessrc kinasecancer |
| spellingShingle | B. Mirza M. H. Sayahi New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions Journal of Sciences, Islamic Republic of Iran ethyl 2,4-dioxo-4-arylbutanoates src kinase cancer |
| title | New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions |
| title_full | New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions |
| title_fullStr | New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions |
| title_full_unstemmed | New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions |
| title_short | New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions |
| title_sort | new homogeneous and robust catalyst for heck and suzuki reactions |
| topic | ethyl 2,4-dioxo-4-arylbutanoates src kinase cancer |
| url | https://jsciences.ut.ac.ir/article_56000_a43391af6fd2ff68d1ec23ee2aac7acd.pdf |
| work_keys_str_mv | AT bmirza newhomogeneousandrobustcatalystforheckandsuzukireactions AT mhsayahi newhomogeneousandrobustcatalystforheckandsuzukireactions |