New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions
In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give th...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Tehran
2015-12-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
| Subjects: | |
| Online Access: | https://jsciences.ut.ac.ir/article_56000_a43391af6fd2ff68d1ec23ee2aac7acd.pdf |
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| Summary: | In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give the corresponding products. All compounds showed moderate activities comparing with staurosporine as the reference drug. |
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| ISSN: | 1016-1104 2345-6914 |