Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management
Purpose. To review the recent neuroimaging studies on cognitive-behavioral therapy (CBT) for pain management, with the aim of exploring possible mechanisms of CBT. Recent Findings. Current studies can be divided into four categories, mixed pain, fibromyalgia, migraine, and experimental pain, based o...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2022/6266619 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850218709462810624 |
|---|---|
| author | Shangyi Bao Mengyuan Qiao Yutong Lu Yunlan Jiang |
| author_facet | Shangyi Bao Mengyuan Qiao Yutong Lu Yunlan Jiang |
| author_sort | Shangyi Bao |
| collection | DOAJ |
| description | Purpose. To review the recent neuroimaging studies on cognitive-behavioral therapy (CBT) for pain management, with the aim of exploring possible mechanisms of CBT. Recent Findings. Current studies can be divided into four categories, mixed pain, fibromyalgia, migraine, and experimental pain, based on the type of disease included, with the same or different changes of brain regions after CBT intervention. According to structural and functional MRI analyses, changes of brain gray matter volume, activation and deactivation of brain regions, and intrinsic connectivity between brain regions were observed after CBT sessions. The brain regions involved mainly included some areas related to cognitive and emotional regulation. After comparison, the DLPFC, OFC, VLPFC, PCC and amygdala were found to be recurrent in multiple studies and may be key regions for CBT intervention in pain management. In the treatment of mixed chronic pain, CBT may decrease the gray matter volume of DLPFC, reduce ICN connection of OFC within the DAN network, and increase fALFF of the PCC. For FM intervention, CBT may activate the bilateral OFC and VLPFC, while in migraine, only the right OFC, VLPFC, and DLPFC were found to be more activated after CBT. In addition, the differential action of the left and right amygdala has also been shown in the latest study of migraine. In heat-evoked pain, CBT may increase the deactivation of the PCC, the connectivity between the DMN and right VLPFC, while diminishing the deactivation of VLPFC. Summary. After CBT, the brain showed stronger top-down pain control, cognitive reassessment, and altered perception of stimulus signals (chronic pain and repeated acute pain). The DLPFC, OFC, VLPFC, PCC, and amygdala may be the key brain regions in CBT intervention of pain. |
| format | Article |
| id | doaj-art-2d63fbc1111e45eeb7e4de1913a1e864 |
| institution | OA Journals |
| issn | 1918-1523 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-2d63fbc1111e45eeb7e4de1913a1e8642025-08-20T02:07:38ZengWileyPain Research and Management1918-15232022-01-01202210.1155/2022/6266619Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain ManagementShangyi Bao0Mengyuan Qiao1Yutong Lu2Yunlan Jiang3Department of HematologyDepartment of GeriatricsSchool of NursingDepartment of NursingPurpose. To review the recent neuroimaging studies on cognitive-behavioral therapy (CBT) for pain management, with the aim of exploring possible mechanisms of CBT. Recent Findings. Current studies can be divided into four categories, mixed pain, fibromyalgia, migraine, and experimental pain, based on the type of disease included, with the same or different changes of brain regions after CBT intervention. According to structural and functional MRI analyses, changes of brain gray matter volume, activation and deactivation of brain regions, and intrinsic connectivity between brain regions were observed after CBT sessions. The brain regions involved mainly included some areas related to cognitive and emotional regulation. After comparison, the DLPFC, OFC, VLPFC, PCC and amygdala were found to be recurrent in multiple studies and may be key regions for CBT intervention in pain management. In the treatment of mixed chronic pain, CBT may decrease the gray matter volume of DLPFC, reduce ICN connection of OFC within the DAN network, and increase fALFF of the PCC. For FM intervention, CBT may activate the bilateral OFC and VLPFC, while in migraine, only the right OFC, VLPFC, and DLPFC were found to be more activated after CBT. In addition, the differential action of the left and right amygdala has also been shown in the latest study of migraine. In heat-evoked pain, CBT may increase the deactivation of the PCC, the connectivity between the DMN and right VLPFC, while diminishing the deactivation of VLPFC. Summary. After CBT, the brain showed stronger top-down pain control, cognitive reassessment, and altered perception of stimulus signals (chronic pain and repeated acute pain). The DLPFC, OFC, VLPFC, PCC, and amygdala may be the key brain regions in CBT intervention of pain.http://dx.doi.org/10.1155/2022/6266619 |
| spellingShingle | Shangyi Bao Mengyuan Qiao Yutong Lu Yunlan Jiang Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management Pain Research and Management |
| title | Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management |
| title_full | Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management |
| title_fullStr | Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management |
| title_full_unstemmed | Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management |
| title_short | Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management |
| title_sort | neuroimaging mechanism of cognitive behavioral therapy in pain management |
| url | http://dx.doi.org/10.1155/2022/6266619 |
| work_keys_str_mv | AT shangyibao neuroimagingmechanismofcognitivebehavioraltherapyinpainmanagement AT mengyuanqiao neuroimagingmechanismofcognitivebehavioraltherapyinpainmanagement AT yutonglu neuroimagingmechanismofcognitivebehavioraltherapyinpainmanagement AT yunlanjiang neuroimagingmechanismofcognitivebehavioraltherapyinpainmanagement |