A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review
Pancreatic lymphoepithelial cyst (LEC) is a rare, benign collection of keratinizing squamous epithelial cells encapsulated by lymphoid tissue. Because of its limited data and nonspecific features that can mimic malignant lesions, LECs can lead to unnecessary operations. A 62-year-old male with a kno...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/4590758 |
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| author | Grace E. Kim Fariha Ramay Stephanie Richards Peter E. Darwin |
| author_facet | Grace E. Kim Fariha Ramay Stephanie Richards Peter E. Darwin |
| author_sort | Grace E. Kim |
| collection | DOAJ |
| description | Pancreatic lymphoepithelial cyst (LEC) is a rare, benign collection of keratinizing squamous epithelial cells encapsulated by lymphoid tissue. Because of its limited data and nonspecific features that can mimic malignant lesions, LECs can lead to unnecessary operations. A 62-year-old male with a known pancreatic mass presented with abdominal pain. CT scan showed an increased mass in the pancreatic head, and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) revealed “rare fragments of benign-appearing squamous epithelium in a background of keratin debris, cyst contents, and scattered lymphocytes,” consistent with a lymphoepithelial cyst. Pancreatic LEC is an extremely rare lesion that comprises of only 0.5% of all pancreatic cysts. EUS-FNA has become the mainstay for diagnosing pancreatic LECs. Given the slow growing and benign nature, conservative management and observation is adequate for pancreatic LECs with excellent long-term outcome. With increasing number of imaging ordered by clinicians, it is anticipated that there will be a greater number of incidental pancreatic LECs detected. Thus, EUS-FNA should be utilized more frequently to help distinguish benign pancreatic LECs from premalignant or malignant lesions to avoid surgery. |
| format | Article |
| id | doaj-art-2d62c234ec2043dbb3506d46c49bc917 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-2d62c234ec2043dbb3506d46c49bc9172025-02-03T01:05:17ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/45907584590758A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and ReviewGrace E. Kim0Fariha Ramay1Stephanie Richards2Peter E. Darwin3University of Maryland Medical Center, Department of Internal Medicine, Baltimore, Maryland, USAUniversity of Maryland School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, Maryland, USAUniversity of Maryland Medical Center, Department of Pathology, Baltimore, Maryland, USAUniversity of Maryland School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, Maryland, USAPancreatic lymphoepithelial cyst (LEC) is a rare, benign collection of keratinizing squamous epithelial cells encapsulated by lymphoid tissue. Because of its limited data and nonspecific features that can mimic malignant lesions, LECs can lead to unnecessary operations. A 62-year-old male with a known pancreatic mass presented with abdominal pain. CT scan showed an increased mass in the pancreatic head, and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) revealed “rare fragments of benign-appearing squamous epithelium in a background of keratin debris, cyst contents, and scattered lymphocytes,” consistent with a lymphoepithelial cyst. Pancreatic LEC is an extremely rare lesion that comprises of only 0.5% of all pancreatic cysts. EUS-FNA has become the mainstay for diagnosing pancreatic LECs. Given the slow growing and benign nature, conservative management and observation is adequate for pancreatic LECs with excellent long-term outcome. With increasing number of imaging ordered by clinicians, it is anticipated that there will be a greater number of incidental pancreatic LECs detected. Thus, EUS-FNA should be utilized more frequently to help distinguish benign pancreatic LECs from premalignant or malignant lesions to avoid surgery.http://dx.doi.org/10.1155/2020/4590758 |
| spellingShingle | Grace E. Kim Fariha Ramay Stephanie Richards Peter E. Darwin A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review Case Reports in Medicine |
| title | A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review |
| title_full | A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review |
| title_fullStr | A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review |
| title_full_unstemmed | A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review |
| title_short | A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review |
| title_sort | rare presentation of pancreatic lymphoepithelial cyst a case report and review |
| url | http://dx.doi.org/10.1155/2020/4590758 |
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