Tolerability for older, persistence for younger: a real-world evidence on sacubitril/valsartan in an Asian heart failure cohort across age

Tolerability for older, persistence for younger: a real-world evidence on sacubitril/valsartan in an Asian heart failure cohort across age

BackgroundSacubitril/Valsartan (S/V) benefits patients with heart failure with reduced ejection fraction (HFrEF), but its tolerability and clinical outcomes across age groups, especially the elderly, remain unclear. This real-world study evaluates these factors in an Asian cohort.MethodsThis retrosp...

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Bibliographic Details
Main Authors: Po-Kai Chan, Chu-Yu Hsu, Chao-Chin Lee, Fan-Han Yu, Fa-Po Chung, Chia-Te Liao, Jin-Long Huang, Huai-Wen Liang, Ying-Hsiang Lee, Po-Lin Lin, Wei-Ru Chiou, Chien-Yi Hsu, Hung-Yu Chang, Wen-Yu Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
sacubitril/valsartan
age
tolerability
heart failure
real-world study
older patient
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1620266/full
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