Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study
INTRODUCTION: The simultaneous interpretation of serum ferritin level and transferrin saturation has been used as a clinical guide to diagnose genetic hemochromatosis. The Hemochromatosis and Iron Overload Screening (HEIRS) Study screened 101,168 North American participants for serum ferritin level...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2014/698352 |
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| author | Andrew Lim Mark Speechley Paul C Adams |
| author_facet | Andrew Lim Mark Speechley Paul C Adams |
| author_sort | Andrew Lim |
| collection | DOAJ |
| description | INTRODUCTION: The simultaneous interpretation of serum ferritin level and transferrin saturation has been used as a clinical guide to diagnose genetic hemochromatosis. The Hemochromatosis and Iron Overload Screening (HEIRS) Study screened 101,168 North American participants for serum ferritin level and transferrin saturation, and C282Y genotyping for the HFE gene. |
| format | Article |
| id | doaj-art-2d5ab2d191b749ce89e7b7636965b529 |
| institution | OA Journals |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-2d5ab2d191b749ce89e7b7636965b5292025-08-20T02:24:07ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972014-01-0128950250410.1155/2014/698352Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS StudyAndrew Lim0Mark Speechley1Paul C Adams2Department of Medicine, Schulich Interfaculty Program in Public Health, Western University, London, Ontario, CanadaDepartment of Epidemiology & Biostatistics and Schulich Interfaculty Program in Public Health, Western University, London, Ontario, CanadaDepartment of Medicine, Schulich Interfaculty Program in Public Health, Western University, London, Ontario, CanadaINTRODUCTION: The simultaneous interpretation of serum ferritin level and transferrin saturation has been used as a clinical guide to diagnose genetic hemochromatosis. The Hemochromatosis and Iron Overload Screening (HEIRS) Study screened 101,168 North American participants for serum ferritin level and transferrin saturation, and C282Y genotyping for the HFE gene.http://dx.doi.org/10.1155/2014/698352 |
| spellingShingle | Andrew Lim Mark Speechley Paul C Adams Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study Canadian Journal of Gastroenterology and Hepatology |
| title | Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study |
| title_full | Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study |
| title_fullStr | Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study |
| title_full_unstemmed | Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study |
| title_short | Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study |
| title_sort | predicting c282y homozygote genotype for hemochromatosis using serum ferritin and transferrin saturation values from 44 809 participants of the heirs study |
| url | http://dx.doi.org/10.1155/2014/698352 |
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