Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research
ABSTRACT Physical activity (PA) is indispensable for overall health. Sub‐optimal PA is linked to reduced quality of life (QOL) and premature death. In clinical research and therapeutics development, defining aspects of PA that are meaningful to patients and care providers is essential for designing...
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| Format: | Article |
| Language: | English |
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Wiley
2025-04-01
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| Series: | Clinical and Translational Science |
| Online Access: | https://doi.org/10.1111/cts.70191 |
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| author | Candice Taguibao Salma Ajraoui Jake Centra Kieran F. Reid Christina Daskalopoulou Alberto Conde Freniche Alan L. Hamilton Astrid M. H. Horstman Benjamin X. Collins Jessilyn Dunn Elena S. Izmailova |
| author_facet | Candice Taguibao Salma Ajraoui Jake Centra Kieran F. Reid Christina Daskalopoulou Alberto Conde Freniche Alan L. Hamilton Astrid M. H. Horstman Benjamin X. Collins Jessilyn Dunn Elena S. Izmailova |
| author_sort | Candice Taguibao |
| collection | DOAJ |
| description | ABSTRACT Physical activity (PA) is indispensable for overall health. Sub‐optimal PA is linked to reduced quality of life (QOL) and premature death. In clinical research and therapeutics development, defining aspects of PA that are meaningful to patients and care providers is essential for designing tailored interventions, identifying individual contextual factors, and enhancing patient satisfaction and engagement in their own well‐being. As digital health technologies (DHTs) measuring PA rapidly evolve, there is an opportunity to further define concepts. A systematic review of qualitative studies to identify concepts of PA that are meaningful to patients and care providers was conducted. Conditions covered included Parkinson's disease, multiple sclerosis, chronic obstructive pulmonary disease, cancer, Duchenne muscular dystrophy, chronic heart failure, sickle cell disease, osteoarthritis, and sarcopenia. We analyzed studies published in the last 20 years utilizing qualitative or mixed methods techniques to describe aspects of PA that patients want to prevent from worsening or improve. Among the 5228 articles returned, 105 studies were included. Thematic synthesis revealed five meaningful aspects of health (MAH) related to PA: ambulation‐dependent activities, balance‐dependent activities, activities needing upper limb function, changing body positions, and participating in activities of different intensities. Patients also reported PA as important to QOL and influenced by internal and external facilitators and barriers. This research presents new findings related to PA MAHs across various therapeutic areas, which go beyond walking. The findings provide a foundation for defining concepts of interest, measures, and endpoints, with applications in clinical research and care, including patient‐focused development of digitally derived measures. |
| format | Article |
| id | doaj-art-2d586f81e536476bbca0a6a7bdc901c7 |
| institution | OA Journals |
| issn | 1752-8054 1752-8062 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Science |
| spelling | doaj-art-2d586f81e536476bbca0a6a7bdc901c72025-08-20T02:25:09ZengWileyClinical and Translational Science1752-80541752-80622025-04-01184n/an/a10.1111/cts.70191Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative ResearchCandice Taguibao0Salma Ajraoui1Jake Centra2Kieran F. Reid3Christina Daskalopoulou4Alberto Conde Freniche5Alan L. Hamilton6Astrid M. H. Horstman7Benjamin X. Collins8Jessilyn Dunn9Elena S. Izmailova10Digital Medicine Society Boston Massachusetts USAPatient‐Centered Solutions IQVIA Durham North Carolina USADigital Medicine Society Boston Massachusetts USALaboratory of Exercise Physiology and Physical Performance, Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies Brigham and Women's Hospital, Harvard Medical School Boston Massachusetts USAPatient‐Centered Solutions IQVIA Durham North Carolina USANestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A. Lausanne Lausanne SwitzerlandCOPD Foundation Miami Florida USANestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A. Lausanne Lausanne SwitzerlandVanderbilt University Medical Center Nashville Tennessee USADuke University Durham North Carolina USAKoneksa Health New York New York USAABSTRACT Physical activity (PA) is indispensable for overall health. Sub‐optimal PA is linked to reduced quality of life (QOL) and premature death. In clinical research and therapeutics development, defining aspects of PA that are meaningful to patients and care providers is essential for designing tailored interventions, identifying individual contextual factors, and enhancing patient satisfaction and engagement in their own well‐being. As digital health technologies (DHTs) measuring PA rapidly evolve, there is an opportunity to further define concepts. A systematic review of qualitative studies to identify concepts of PA that are meaningful to patients and care providers was conducted. Conditions covered included Parkinson's disease, multiple sclerosis, chronic obstructive pulmonary disease, cancer, Duchenne muscular dystrophy, chronic heart failure, sickle cell disease, osteoarthritis, and sarcopenia. We analyzed studies published in the last 20 years utilizing qualitative or mixed methods techniques to describe aspects of PA that patients want to prevent from worsening or improve. Among the 5228 articles returned, 105 studies were included. Thematic synthesis revealed five meaningful aspects of health (MAH) related to PA: ambulation‐dependent activities, balance‐dependent activities, activities needing upper limb function, changing body positions, and participating in activities of different intensities. Patients also reported PA as important to QOL and influenced by internal and external facilitators and barriers. This research presents new findings related to PA MAHs across various therapeutic areas, which go beyond walking. The findings provide a foundation for defining concepts of interest, measures, and endpoints, with applications in clinical research and care, including patient‐focused development of digitally derived measures.https://doi.org/10.1111/cts.70191 |
| spellingShingle | Candice Taguibao Salma Ajraoui Jake Centra Kieran F. Reid Christina Daskalopoulou Alberto Conde Freniche Alan L. Hamilton Astrid M. H. Horstman Benjamin X. Collins Jessilyn Dunn Elena S. Izmailova Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research Clinical and Translational Science |
| title | Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research |
| title_full | Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research |
| title_fullStr | Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research |
| title_full_unstemmed | Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research |
| title_short | Identifying Concepts of Physical Activity Which Are Clinically Meaningful to Patients and Care Providers: A Systematic Review of Qualitative Research |
| title_sort | identifying concepts of physical activity which are clinically meaningful to patients and care providers a systematic review of qualitative research |
| url | https://doi.org/10.1111/cts.70191 |
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